SCHEMBL22874469

SCHEMBL22874469

c1ccc(Oc2cccc3c2B2c4c(cccc4Oc4c(-c5cc(-c6ccc7oc8ccccc8c7c6)cc(-c6ccc7oc8ccccc8c7c6)c5)ccc(Oc5ccccc5)c42)O3)cc1

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.35
POLB P06746 1/20 0.35
RAB9A P51151 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
PLA2G10 O15496 1/20 0.32
PLA2G2A P14555 1/20 0.32
PLA2G4A P47712 1/20 0.32
MAPT P10636 1/20 0.31
LMNA P02545 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22874264 0.81 PLA2G2A (0.38) NPC1RAB9APLA2G10PLA2G2APLA2G4A
SCHEMBL21302912 0.81 PLA2G2A (0.38) NPC1RAB9APLA2G10PLA2G2APLA2G4A
SCHEMBL22874472 0.77 NPC1 (0.39) NPC1POLBRAB9AL3MBTL1MAPT
SCHEMBL21983014 0.76 MAPT (0.39) NPC1RAB9APLA2G10PLA2G2APLA2G4A
SCHEMBL24306604 0.74 MAPT (0.41) NPC1RAB9APLA2G10PLA2G2APLA2G4A
SCHEMBL22874203 0.72 PLA2G2A (0.34) PLA2G10PLA2G2APLA2G4A
SCHEMBL21793580 0.71 MAPT (0.36) NPC1RAB9APLA2G2APLA2G4AMAPT
SCHEMBL18961061 0.70 MAPT (0.38) NPC1RAB9APLA2G10PLA2G2APLA2G4A
SCHEMBL21793865 0.70 ALOX5 (0.37) NPC1RAB9APLA2G10PLA2G2APLA2G4A
SCHEMBL24307161 0.69 AHR (0.41) NPC1RAB9APLA2G10PLA2G2APLA2G4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210008872-A1 COMPOSITION FOR ELECTRONIC DEVICES, INK FOR ELECTRONIC DEVICES, AND METHOD FOR PRODUCING ELECTRONIC DEVICE Konica Minolta, Inc. (JP) 2021-01-14 US disclosed