Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 11/20 | 0.68 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.58 |
| ▸ | APP | P05067 | 1/20 | 0.58 |
| ▸ | IDO1 | P14902 | 2/20 | 0.56 |
| ▸ | AGXT | P21549 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23720 | 0.92 | MAOB (0.60) | MAOBMRGPRX4APPIDO1AGXT | |
| SCHEMBL22564 | 0.87 | MAOB (0.64) | MAOBAPPNPC1RAB9ABCHE | |
| SCHEMBL22316 | 0.83 | MAOB (0.66) | MAOBBCHEMEN1KMT2A | |
| SCHEMBL16710547 | 0.83 | MAOB (0.71) | MAOBMRGPRX4APPIDO1AGXT | |
| SCHEMBL22274 | 0.82 | ACHE (0.54) | MAOBIDO1AGXTNPC1RAB9A | |
| SCHEMBL30238353 | 0.82 | ACHE (0.54) | MAOBIDO1AGXTNPC1RAB9A | |
| SCHEMBL13462942 | 0.81 | MAOB (0.69) | MAOBMRGPRX4APPIDO1AGXT | |
| SCHEMBL13263642 | 0.81 | MAOB (0.79) | MAOBMRGPRX4IDO1AGXTRAB9A | |
| SCHEMBL791569 | 0.81 | MAOB (1.00) | MAOBMRGPRX4APPABCB1HTR1A | |
| SCHEMBL14547318 | 0.81 | MAOB (0.81) | MAOBMRGPRX4IDO1AGXTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2609089-A1 | SELECTIVE 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 INHIBITORS | Universität des Saarlandes (DE) | 2013-07-03 | — | — | EP | disclosed |
| WO-2012025638-A1 | SELECTIVE 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 INHIBITORS | Universität des Saarlandes (DE) | 2012-03-01 | — | — | WO | disclosed |