Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 2/20 | 0.49 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.49 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.49 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.46 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.46 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | FBP1 | P09467 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.46 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.46 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.46 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22875603 | 0.89 | P2RY1 (0.55) | P2RX3P2RX4P2RX2P2RX1DNPH1 | |
| SCHEMBL22875410 | 0.89 | EGFR (0.51) | EHMT1RXFP1 | |
| SCHEMBL22875450 | 0.89 | EGFR (0.51) | EHMT1RXFP1 | |
| SCHEMBL22875579 | 0.80 | POLB (0.49) | DNPH1PRKAB2TRPM2LDHAADRB2 | |
| SCHEMBL22875605 | 0.80 | P2RY1 (0.70) | P2RX3P2RX4P2RX2P2RX1DNPH1 | |
| SCHEMBL18340532 | 0.80 | DNPH1 (0.68) | DNPH1PRKAB2TRPM2LDHAADRB2 | |
| SCHEMBL22875576 | 0.77 | EHMT1 (0.60) | EHMT1RXFP1 | |
| SCHEMBL22875787 | 0.77 | EHMT1 (0.60) | EHMT1RXFP1 | |
| SCHEMBL11682736 | 0.76 | P2RX3 (0.49) | P2RX3P2RX4P2RX2P2RX1P2RX7 | |
| SCHEMBL22875571 | 0.76 | EGFR (0.46) | EHMT1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210007999-A1 | NANOPARTICLE COMPOSITIONS | JANUARY THERAPEUTICS, INC. | 2021-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210007999-A1 | NANOPARTICLE COMPOSITIONS | PNP, NTPCR, TYMP | P2RX3 717/4885P2RX4 941/4885P2RX2 1095/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.