Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | HAT1 | O14929 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23659225 | 0.89 | MAPT (0.41) | MAPTKDM4EL3MBTL1ALDH1A1LMNA | |
| SCHEMBL23656504 | 0.86 | ALDH1A1 (0.48) | MAPTKDM4EL3MBTL1ALDH1A1LMNA | |
| SCHEMBL22876029 | 0.86 | KDM4E (0.45) | MAPTKDM4EL3MBTL1ALDH1A1LMNA | |
| SCHEMBL22875744 | 0.84 | MTNR1A (0.43) | MAPTKDM4EL3MBTL1ALDH1A1LMNA | |
| SCHEMBL24769839 | 0.84 | SOS2 (0.47) | MAPTKDM4EL3MBTL1ALDH1A1LMNA | |
| SCHEMBL23666194 | 0.81 | SCN9A (0.50) | MAPTKDM4EL3MBTL1ALDH1A1LMNA | |
| SCHEMBL22875748 | 0.81 | MAPT (0.43) | MAPTKDM4EL3MBTL1ALDH1A1LMNA | |
| SCHEMBL19007004 | 0.77 | SOS2 (0.46) | MAPTKDM4EL3MBTL1ALDH1A1LMNA | |
| SCHEMBL21644783 | 0.77 | MAPT (0.59) | MAPTMEN1HCRTR1KMT2ATP53 | |
| SCHEMBL21644784 | 0.77 | MAPT (0.59) | MAPTMEN1HCRTR1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021007433-A1 | PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES | PROTAGONIST THERAPEUTICS, INC. (US) | 2021-01-14 | — | — | WO | disclosed |