SCHEMBL22876115

SCHEMBL22876115

CC1(C)c2ccccc2-c2cc(-c3nc(-c4ccccc4)nc(-c4cccc(-c5cccc6oc7ccc(-c8ccc(-c9ccccc9)cc8)cc7c56)c4)n3)ccc21

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 1/20 0.35
CSNK2A2 P19784 1/20 0.35
CSNK2B P67870 1/20 0.35
PIM3 Q86V86 1/20 0.35
PIM2 Q9P1W9 1/20 0.35
PLA2G2A P14555 4/20 0.34
PLA2G4A P47712 4/20 0.34
PLA2G10 O15496 1/20 0.34
GAA P10253 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CASP3 P42574 1/20 0.33
SENP7 Q9BQF6 1/20 0.33
SENP6 Q9GZR1 1/20 0.33
PRKDC P78527 1/20 0.31
MAPT P10636 4/20 0.31
KMT2A Q03164 4/20 0.31
ALDH1A1 P00352 3/20 0.31
MEN1 O00255 3/20 0.31
HPGD P15428 2/20 0.31
TERT O14746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19802205 1.00 PIM1 (0.35) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL19802533 0.96 PLA2G2A (0.34) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL22876269 0.95 PLA2G2A (0.35) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL19802174 0.95 PLA2G2A (0.34) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL19803096 0.95 PLA2G2A (0.34) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL22876489 0.94 PIM1 (0.34) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL26287354 0.94 PLA2G2A (0.31) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL22876217 0.93 KDM4E (0.34) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL19802763 0.93 PIM1 (0.31) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL19802737 0.92 CASP3 (0.34) PIM1CSNK2A2CSNK2BPIM3PIM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11685859-B2 Organic light emitting device LG CHEM, LTD. (KR) 2023-06-27 US disclosed
US-11685859-B2 Organic light emitting device LG CHEM, LTD. (KR) 2023-06-27 US disclosed
US-20210009894-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2021-01-14 US disclosed