SCHEMBL228776

SCHEMBL228776

CC[SiH2]OC(OC)(OC)OC

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5014130 0.78
SCHEMBL28056397 0.74 ALDH1A1 (0.35) ALDH1A1TSHRTDP1
SCHEMBL706456 0.69
SCHEMBL225593 0.69
SCHEMBL229485 0.65
SCHEMBL4266461 0.65
SCHEMBL703738 0.63
SCHEMBL11805653 0.63
SCHEMBL46522 0.60
SCHEMBL2639479 0.58

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8623958-B2 Oil-in-water silicone emulsion composition DOW CORNING TORAY CO. LTD. (JP) 2014-01-07 US disclosed
EP-2406323-B1 OIL-IN-WATER SILICONE EMULSION COMPOSITION DOW CORNING TORAY CO LTD (JP) 2013-07-24 EP disclosed
EP-2406322-A2 OIL-IN-WATER SILICONE EMULSION COMPOSITION Dow Corning Toray Co., Ltd. (JP) 2012-01-18 EP disclosed
EP-2406323-A2 OIL-IN-WATER SILICONE EMULSION COMPOSITION Dow Corning Toray Co., Ltd. (JP) 2012-01-18 EP disclosed
US-20120004354-A1 Oil-In-Water Silicone Emulsion Composition DOW TORAY CO., LTD. (JP) 2012-01-05 US disclosed
US-20110319557-A1 Oil-In-Water Silicone Emulsion Composition DOW CORNING TORAY CO., LTD. (JP) 2011-12-29 US disclosed
WO-2010104186-A2 OIL-IN-WATER SILICONE EMULSION COMPOSITION DOW CORNING TORAY CO., LTD. (JP) 2010-09-16 WO disclosed
WO-2010104185-A2 OIL-IN-WATER SILICONE EMULSION COMPOSITION DOW CORNING TORAY CO., LTD. (JP) 2010-09-16 WO disclosed