Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.44 |
| ▸ | OGA | O60502 | 6/20 | 0.43 |
| ▸ | TIPARP | Q7Z3E1 | 8/20 | 0.42 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | TNKS | O95271 | 1/20 | 0.38 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | PARP12 | Q9H0J9 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19457343 | 0.86 | OGA (0.44) | GPR119OGATIPARPCXCR3ACACB | |
| SCHEMBL19450528 | 0.84 | OGA (0.43) | GPR119OGATIPARPCXCR3ACACB | |
| SCHEMBL19435030 | 0.82 | OGA (0.45) | GPR119OGATIPARPPARP1ACACB | |
| SCHEMBL19435009 | 0.82 | OGA (0.45) | GPR119OGATIPARPPARP1ACACB | |
| SCHEMBL19434300 | 0.82 | OGA (0.45) | GPR119OGATIPARPPARP1ACACB | |
| SCHEMBL26124908 | 0.79 | SMN1; SMN2 (0.46) | GPR119TIPARPACACBPPARGPPARD | |
| SCHEMBL26121974 | 0.77 | PPARG (0.44) | GPR119OGATIPARPPARP1PPARG | |
| SCHEMBL26126273 | 0.77 | ACACB (0.45) | OGATIPARPACACBPPARGPPARD | |
| SCHEMBL26126441 | 0.77 | ACACB (0.45) | OGATIPARPPARP1ACACBPPARG | |
| SCHEMBL28982910 | 0.76 | LMNA (0.46) | GPR119OGATIPARPPARP1ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021005436-A1 | COMBINATION THERAPY OF GPR119 AGONISTS AND DPP-4 INHIBITORS | MANKIND PHARMA LTD. (IN) | 2021-01-14 | — | — | WO | disclosed |