Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 6/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.40 |
| ▸ | TIPARP | Q7Z3E1 | 4/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | LCAT | P04180 | 1/20 | 0.38 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19457343 | 0.86 | OGA (0.44) | OGAGPR119TIPARPACACBLCAT | |
| SCHEMBL22878533 | 0.84 | GPR119 (0.44) | OGAGPR119TIPARPACACBPPARG | |
| SCHEMBL19434300 | 0.82 | OGA (0.45) | OGAGPR119TIPARPACACBLCAT | |
| SCHEMBL19435009 | 0.82 | OGA (0.45) | OGAGPR119TIPARPACACBLCAT | |
| SCHEMBL19435030 | 0.82 | OGA (0.45) | OGAGPR119TIPARPACACBLCAT | |
| SCHEMBL19450522 | 0.80 | NPC1 (0.48) | GPR119ACACB | |
| SCHEMBL19457397 | 0.80 | ACACB (0.36) | GPR119TIPARPACACBPPARGPPARD | |
| SCHEMBL26126273 | 0.77 | ACACB (0.45) | OGATIPARPACACBPPARGPPARD | |
| SCHEMBL26126441 | 0.77 | ACACB (0.45) | OGATIPARPACACBPPARGPPARD | |
| SCHEMBL28982910 | 0.76 | LMNA (0.46) | OGAGPR119TIPARPACACBLCAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10954229-B2 | GPR119 agonist compounds | MANKIND PHARMA LTD. (IN) | 2021-03-23 | — | — | US | disclosed |
| US-20200317661-A1 | NOVEL GPR119 AGONIST COMPOUNDS | MANKIND PHARMA LTD. (IN) | 2020-10-08 | — | — | US | disclosed |
| US-10752622-B2 | GPR119 agonist compounds | MANKIND PHARMA LTD. (IN) | 2020-08-25 | — | — | US | disclosed |
| US-20190127363-A1 | NOVEL GPR119 AGONIST COMPOUNDS | MANKIND PHARMA LTD. (IN) | 2019-05-02 | — | — | US | disclosed |
| US-20170291894-A1 | NOVEL GPR119 AGONIST COMPOUNDS | MANKIND PHARMA LTD. (IN) | 2017-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200317661-A1 | NOVEL GPR119 AGONIST COMPOUNDS | GPR119, GPR84, GPR88 | OGA 3394/4885GPR119 1/4885TIPARP 3156/4885 |
| US-20170291894-A1 | NOVEL GPR119 AGONIST COMPOUNDS | GPR119, GPR84, GPR88 | OGA 3394/4885GPR119 1/4885TIPARP 3156/4885 |
| US-10752622-B2 | GPR119 agonist compounds | GPR119, GPR84, GPR65 | OGA 2895/4885GPR119 1/4885TIPARP 3279/4885 |
| US-10954229-B2 | GPR119 agonist compounds | GPR119, GPR84, GPR65 | OGA 2895/4885GPR119 1/4885TIPARP 3279/4885 |
| US-20190127363-A1 | NOVEL GPR119 AGONIST COMPOUNDS | GPR119, GPR84, GPR88 | OGA 3394/4885GPR119 1/4885TIPARP 3156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.