Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.34 |
| ▸ | SDHB | P21912 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2283184 | 0.74 | TLR8 (0.35) | TLR8L3MBTL1 | |
| SCHEMBL27743731 | 0.74 | TLR8 (0.33) | TLR8 | |
| SCHEMBL2285690 | 0.73 | MBOAT4 (0.35) | TLR8 | |
| SCHEMBL4355851 | 0.69 | SLC22A12 (0.38) | SDHBSMN1; SMN2L3MBTL1 | |
| SCHEMBL4194121 | 0.69 | — | — | |
| SCHEMBL4195166 | 0.69 | GLP1R (0.31) | — | |
| SCHEMBL2286205 | 0.67 | TLR8 (0.33) | TLR8 | |
| SCHEMBL2286212 | 0.66 | TLR8 (0.32) | TLR8 | |
| SCHEMBL12036842 | 0.64 | SMN1; SMN2 (0.35) | SMN1; SMN2L3MBTL1 | |
| SCHEMBL18067288 | 0.64 | LMNA (0.35) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110201496-A1 | Substituted 5-Hetaryl-4-Aminopyrimidines | BASF AKTIENGESELLSCHAFT (DE) | 2011-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110201496-A1 | Substituted 5-Hetaryl-4-Aminopyrimidines | CBR3, CBR1, CYC1 | TLR8 1853/4885SDHB 3353/4885SMN1; SMN2 4050/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.