SCHEMBL22880644

SCHEMBL22880644

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nearest known ligand 0.64

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 17/20 0.64
NAALAD2 Q9Y3Q0 2/20 0.64
RIMKLA Q8IXN7 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13944967 0.91 FOLH1 (0.68) FOLH1NAALAD2RIMKLA
SCHEMBL23468425 0.91 FOLH1 (0.68) FOLH1NAALAD2RIMKLA
SCHEMBL16518793 0.88 FOLH1 (0.70) FOLH1NAALAD2RIMKLA
SCHEMBL16378657 0.88 FOLH1 (0.65) FOLH1NAALAD2RIMKLA
SCHEMBL22536141 0.85 FOLH1 (0.66) FOLH1NAALAD2RIMKLA
SCHEMBL18655461 0.85 FOLH1 (0.74) FOLH1NAALAD2RIMKLA
SCHEMBL20993564 0.84 FOLH1 (0.71) FOLH1NAALAD2RIMKLA
SCHEMBL16374702 0.84 FOLH1 (0.64) FOLH1NAALAD2RIMKLA
SCHEMBL20018409 0.84 FOLH1 (0.64) FOLH1NAALAD2RIMKLA
SCHEMBL16122936 0.84 FOLH1 (0.60) FOLH1NAALAD2RIMKLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3347019-B1 PSMA-TARGETED NIR DYES AND THEIR USES ON TARGET LABORATORIES LLC (US) 2021-01-13 EP disclosed