Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 4/20 | 0.46 |
| ▸ | F3 | P13726 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29992371 | 0.99 | LMNA (0.52) | LMNATDP1SMN1; SMN2HDAC8HDAC6 | |
| SCHEMBL22882127 | 0.91 | LMNA (0.64) | LMNATDP1SMN1; SMN2HDAC8HDAC6 | |
| Hydrochloric Acid SCHEMBL28536897 | 0.90 | LMNA (0.62) | LMNATDP1SMN1; SMN2HDAC8HDAC6 | |
| SCHEMBL22882008 | 0.87 | LMNA (0.58) | LMNATDP1SMN1; SMN2HDAC8HDAC6 | |
| Hydrochloric Acid SCHEMBL29992806 | 0.86 | LMNA (0.60) | LMNATDP1SMN1; SMN2HDAC8HDAC6 | |
| SCHEMBL22881928 | 0.85 | LMNA (0.51) | LMNATDP1SMN1; SMN2HDAC8HDAC6 | |
| SCHEMBL28529970 | 0.84 | AKR1B10 (0.54) | LMNATDP1SMN1; SMN2HDAC8HDAC6 | |
| Hydrochloric Acid SCHEMBL28546543 | 0.83 | AKR1B10 (0.52) | LMNATDP1SMN1; SMN2HDAC8HDAC6 | |
| SCHEMBL28812187 | 0.83 | LMNA (0.70) | LMNATDP1SMN1; SMN2HDAC8HDAC6 | |
| SCHEMBL24090214 | 0.82 | GAA (0.48) | LMNATDP1SMN1; SMN2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210380727-A1 | NOVEL PHOTOCROSSLINKABLE ALGINIC ACID DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2021-12-09 | — | — | US | disclosed |
| EP-3760647-A1 | NOVEL PHOTOCROSSLINKABLE ALGINIC ACID DERIVATIVE | Mochida Pharmaceutical Co., Ltd. (JP) | 2021-01-06 | — | — | EP | disclosed |