SCHEMBL22883197

SCHEMBL22883197

Cc1cccc(-c2cccc(-c3cc(Cl)nc(-c4ccccc4)n3)c2)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.58
KDM4E B2RXH2 4/20 0.46
HSP90AA1 P07900 1/20 0.46
HSP90AB1 P08238 1/20 0.46
RAB9A P51151 1/20 0.46
DPP4 P27487 1/20 0.46
MAPT P10636 4/20 0.45
MEN1 O00255 4/20 0.45
KMT2A Q03164 4/20 0.45
L3MBTL1 Q9Y468 3/20 0.45
ALDH1A1 P00352 3/20 0.45
HPGD P15428 3/20 0.45
TDP1 Q9NUW8 1/20 0.45
IDO1 P14902 1/20 0.44
METAP2 P50579 1/20 0.44
NR1I3 Q14994 1/20 0.43
ATP4A P20648 1/20 0.43
ATP4B P51164 1/20 0.43
DHODH Q02127 1/20 0.42
POLB P06746 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4546922 0.89 RAB9A (0.53) LMNAKDM4ERAB9ADPP4MAPT
SCHEMBL4546972 0.89 RAB9A (0.53) LMNAKDM4ERAB9ADPP4MAPT
SCHEMBL30322675 0.89 LMNA (0.58) LMNAKDM4EHSP90AA1HSP90AB1MAPT
SCHEMBL4546911 0.89 RAB9A (0.53) LMNAKDM4ERAB9ADPP4MAPT
SCHEMBL17412384 0.89 LMNA (0.58) LMNAKDM4EHSP90AA1HSP90AB1MAPT
SCHEMBL10128354 0.89 RAB9A (0.53) LMNAKDM4ERAB9ADPP4MAPT
SCHEMBL17412386 0.87 LMNA (0.56) LMNAKDM4EHSP90AA1HSP90AB1MAPT
SCHEMBL12936803 0.87 MEN1 (0.54) LMNAKDM4ERAB9ADPP4MAPT
SCHEMBL18731951 0.87 RAB9A (0.51) LMNAKDM4ERAB9ADPP4MAPT
SCHEMBL4546921 0.85 RAB9A (0.50) LMNAKDM4ERAB9ADPP4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11152576-B2 Organic light emitting device LG CHEM, LTD. (KR) 2021-10-19 US disclosed
US-20210013422-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2021-01-14 US disclosed