Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | NOX1 | Q9Y5S8 | 3/20 | 0.49 |
| ▸ | CYBB | P04839 | 1/20 | 0.49 |
| ▸ | NOX3 | Q9HBY0 | 1/20 | 0.49 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.49 |
| ▸ | JUN | P05412 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.41 |
| ▸ | RELA | Q04206 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20842835 | 0.81 | NOX1 (0.68) | MAPTUSP2GAANOX1CYBB | |
| SCHEMBL30811565 | 0.73 | NOX1 (0.84) | MAPTUSP2GAANOX1CYBB | |
| SCHEMBL10372692 | 0.73 | NOX1 (0.84) | MAPTUSP2GAANOX1CYBB | |
| SCHEMBL19744465 | 0.72 | NOX1 (0.57) | MAPTUSP2GAANOX1CYBB | |
| SCHEMBL19744471 | 0.72 | NOX1 (0.57) | MAPTUSP2GAANOX1CYBB | |
| SCHEMBL25141279 | 0.72 | NOX1 (0.64) | MAPTUSP2GAANOX1CYBB | |
| SCHEMBL20923876 | 0.71 | MAPT (0.43) | MAPTUSP2GAANOX1HPGD | |
| Hydrochloric Acid SCHEMBL8957250 | 0.71 | NOX1 (0.62) | MAPTUSP2GAANOX1CYBB | |
| SCHEMBL11375009 | 0.69 | NOX1 (0.69) | MAPTUSP2GAANOX1CYBB | |
| SCHEMBL20444601 | 0.67 | NOX1 (0.54) | MAPTUSP2GAANOX1CYBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3459944-B1 | AZEPANYL-DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME WITH ANTIPARASITIC ACTIVITY | MERCK PATENT GMBH (DE) | 2021-01-06 | — | — | EP | disclosed |