Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 12/20 | 0.69 |
| ▸ | CYBB | P04839 | 2/20 | 0.69 |
| ▸ | NOX3 | Q9HBY0 | 2/20 | 0.69 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 5/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | JUN | P05412 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20842835 | 0.85 | NOX1 (0.68) | NOX1CYBBNOX3NOX4MAPT | |
| Phenothiazine SCHEMBL6532335 | 0.82 | NOX1 (1.00) | NOX1CYBBNOX3NOX4MAPT | |
| SCHEMBL560225 | 0.82 | NOX1 (1.00) | NOX1CYBBNOX3NOX4MAPT | |
| SCHEMBL29475150 | 0.82 | NOX1 (1.00) | NOX1CYBBNOX3NOX4MAPT | |
| SCHEMBL342918 | 0.81 | NOX1 (0.81) | NOX1CYBBNOX3NOX4MAPT | |
| Benzene SCHEMBL29242186 | 0.81 | NOX1 (0.97) | NOX1CYBBNOX3NOX4MAPT | |
| SCHEMBL30811565 | 0.80 | NOX1 (0.84) | NOX1CYBBNOX3NOX4MAPT | |
| SCHEMBL10372692 | 0.80 | NOX1 (0.84) | NOX1CYBBNOX3NOX4MAPT | |
| SCHEMBL23059883 | 0.78 | NOX1 (0.69) | NOX1CYBBNOX3NOX4MAPT | |
| SCHEMBL6676353 | 0.77 | NOX1 (1.00) | NOX1CYBBNOX3NOX4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4249003-A | Process for polycyclic amines | AKTIEBOLAGET LEO (SE) | 1981-02-03 | — | — | US | claimed |