SCHEMBL2288609

SCHEMBL2288609

CCCCCCCCCCCCCCCCC[CH]CCC[Si](OC)(OC)OC

nearest known ligand 0.53

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.53
TSHR P16473 3/20 0.38
FAAH O00519 2/20 0.34
TRPV1 Q8NER1 1/20 0.34
LPAR2 Q9HBW0 2/20 0.34
LPAR3 Q9UBY5 2/20 0.34
LPAR1 Q92633 1/20 0.34
THRB P10828 1/20 0.33
DNM1 Q05193 3/20 0.32
EPHX1 P07099 1/20 0.31
EP300 Q09472 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2713409 0.94 LMNA (0.49) LMNAFAAHTRPV1LPAR2LPAR3
SCHEMBL28079022 0.92 LMNA (0.48) LMNATSHRFAAHTRPV1LPAR2
SCHEMBL28278295 0.87 LMNA (0.39) LMNA
SCHEMBL2713411 0.83 LMNA (0.53) LMNAFAAHTRPV1LPAR2LPAR3
SCHEMBL28079118 0.83 LMNA (0.42) LMNATSHR
SCHEMBL35912 0.82 LMNA (0.65) LMNATSHRTHRBDNM1EPHX1
SCHEMBL304612 0.82 LMNA (0.65) LMNATSHRTHRBDNM1EPHX1
Hexane SCHEMBL6049081 0.82 LMNA (0.65) LMNATSHRTHRBDNM1EPHX1
SCHEMBL6756329 0.82 LMNA (0.65) LMNATSHRTHRBDNM1EPHX1
SCHEMBL1780545 0.82 LMNA (0.65) LMNATSHRTHRBDNM1EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4323518-B2 2009-09-02 JP claimed
JP-2006526686-A 2006-11-24 JP claimed
EP-1678266-A2 A CLEANING AND MULTIFUNCTIONAL COATING COMPOSITION CONTAINING AN ORGANOSILANE QUATERNARY COMPOUND AND METHODS OF USING Resource Development L.L.C. (US) 2006-07-12 EP claimed
WO-2005042657-A2 A CLEANING AND MULTIFUNCTIONAL COATING COMPOSITION CONTAINING AN ORGANOSILANE QUATERNARY COMPOUND AND METHODS OF USING RESOURCE DEVELOPMENT L.L.C. (US) 2005-05-12 WO claimed
US-8263153-B2 Method of preventing or reducing haze in a beverage using silane-treated silica filter media DOW CORNING CORPORATION (US) 2012-09-11 US disclosed
US-7989010-B2 Method of reducing off-flavor in a beverage using silane-treated silica filter media DOW CORNING CORPORATION (US) 2011-08-02 US disclosed
US-7850012-B2 Silane-treated silica filter media DOW CORNING CORPORATION (US) 2010-12-14 US disclosed
US-20090232950-A1 METHOD OF PREVENTING OR REDUCING OFF-FLAVOR IN A BEVERAGE USING SILANE-TREATED SILICA FILTER MEDIA DOW CORNING CORPORATION 2009-09-17 US disclosed
US-20090214701-A1 Method of preventing or reducing haze in a beverage using silane-treated silica filter media DOW CORNING CORPORATION 2009-08-27 US disclosed
US-20080185333-A1 SILANE-TREATED SILICA FILTER MEDIA DOW CORNING CORPORATION 2008-08-07 US disclosed
US-7374684-B2 Method of separating components in a sample using silane-treated silica filter media DOW CORNING CORPORATION (US) 2008-05-20 US disclosed
US-20070267349-A1 METHOD OF SEPARATING COMPONENTS IN A SAMPLE USING SILANE-TREATED SILICA FILTER MEDIA DOW CORNING CORPORATION 2007-11-22 US disclosed
US-7264728-B2 Method of separating components in a sample using silane-treated silica filter media DOW CORNING CORPORATION (US) 2007-09-04 US disclosed
WO-2007061625-A2 A THERAPEUTIC COMPOSITION CONTAINING AN ORGANOSILANE QUATERNARY COMPOUND AND HYDROGEN PEROXIDE FOR TREATING SKIN DISORDERS RESOURCE DEVELOPMENT L.L.C. (US) 2007-05-31 WO disclosed
US-6986857-B2 Method for preparing a mold part useful for transferring a coating onto an optical substrate ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) 2006-01-17 US disclosed
US-6890458-B2 Method for forming on-site a coated optical article ESSILOR INTERNATIONAL COMPAGNIE GENERAL D'OPTIQUE (FR) 2005-05-10 US disclosed
US-6887402-B2 Method for transferring from a mold a hydrophobic top coat onto an optical substrate ESSILOR INTERNATIONAL COMPAGNIE GENERAL D'OPTIQUE (FR) 2005-05-03 US disclosed
US-20050029195-A1 Method of separating components in a sample using silane-treated silica filter media DOW CORNING CORPORATION 2005-02-10 US disclosed