SCHEMBL28079022

SCHEMBL28079022

CCCCCC[CH]CC[Si](OC)(OC)OC

nearest known ligand 0.48

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.48
TSHR P16473 3/20 0.38
FAAH O00519 2/20 0.34
TRPV1 Q8NER1 1/20 0.34
LPAR2 Q9HBW0 2/20 0.34
LPAR3 Q9UBY5 2/20 0.34
LPAR1 Q92633 1/20 0.34
THRB P10828 1/20 0.33
DNM1 Q05193 3/20 0.32
EPHX1 P07099 1/20 0.31
EP300 Q09472 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2288609 0.92 LMNA (0.53) LMNATSHRFAAHTRPV1LPAR2
SCHEMBL28079118 0.91 LMNA (0.42) LMNATSHR
SCHEMBL2713409 0.86 LMNA (0.49) LMNAFAAHTRPV1LPAR2LPAR3
SCHEMBL28044097 0.82 LMNA (0.36) LMNA
SCHEMBL114003 0.77 LMNA (0.65) LMNATSHRTHRBDNM1EPHX1
SCHEMBL57462 0.77 LMNA (0.65) LMNATSHRTHRBDNM1EPHX1
SCHEMBL818064 0.77 LMNA (0.65) LMNATSHRTHRBDNM1EPHX1
SCHEMBL17003993 0.77 LMNA (0.65) LMNATSHRTHRBDNM1EPHX1
SCHEMBL57407 0.77 LMNA (0.65) LMNATSHRTHRBDNM1EPHX1
SCHEMBL817813 0.77 LMNA (0.65) LMNATSHRTHRBDNM1EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106062044-A Polysiloxane copolymer, and antistatic agent and resin composition containing same 信越化学工业株式会社 2016-10-26 CN disclosed
CN-105916913-A Polysiloxane copolymer and antistatic agent comprising same 广荣化学工业株式会社 2016-08-31 CN disclosed