Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 19/20 | 0.46 |
| ▸ | DCAF1 | Q9Y4B6 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22886386 | 0.95 | CAPN1 (0.49) | CAPN1 | |
| SCHEMBL22886401 | 0.94 | CAPN1 (0.45) | CAPN1DCAF1 | |
| SCHEMBL21854248 | 0.91 | CAPN1 (0.57) | CAPN1CTSS | |
| SCHEMBL20027773 | 0.91 | CAPN1 (0.57) | CAPN1CTSS | |
| SCHEMBL21854128 | 0.91 | CAPN1 (0.57) | CAPN1CTSS | |
| SCHEMBL22886550 | 0.89 | CAPN1 (0.44) | CAPN1DCAF1 | |
| SCHEMBL22886525 | 0.88 | CAPN1 (0.41) | CAPN1CTSS | |
| SCHEMBL22886394 | 0.87 | CAPN1 (0.48) | CAPN1CTSS | |
| SCHEMBL22886823 | 0.87 | L3MBTL1 (0.43) | CAPN1 | |
| SCHEMBL22886500 | 0.86 | DCAF1 (0.54) | CAPN1DCAF1CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210009564-A1 | CALPAIN MODULATORS AND THERAPEUTIC USES THEREOF | BLADE THERAPERTICS INC (US) | 2021-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210009564-A1 | CALPAIN MODULATORS AND THERAPEUTIC USES THEREOF | CAPNS1, CAPN9, CAPN1 | CAPN1 3/4885DCAF1 2355/4885CTSS 177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.