SCHEMBL2288747

SCHEMBL2288747

Clc1ccc(-c2ccc(Cl)c(Cl)c2Cl)cc1

nearest known ligand 0.64

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
AHR P35869 8/20 0.64
LMNA P02545 1/20 0.40
CYP2A6 P11509 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.39
MAPK1 P28482 1/20 0.39
PTGS2 P35354 2/20 0.38
TDO2 P48775 1/20 0.36
TP53 P04637 1/20 0.36
CYP1B1 Q16678 1/20 0.36
PTGS1 P23219 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2097022 0.81 AHR (0.59) AHRCYP2A6CYP3A4MAPK1PTGS2
SCHEMBL29983843 0.80 AHR (0.60) AHRCYP2A6CYP1A2CYP3A4MAPK1
SCHEMBL381602 0.80 AHR (0.60) AHRCYP2A6CYP1A2CYP3A4MAPK1
SCHEMBL6469995 0.79 AHR (0.47) AHRLMNACYP2A6CYP1A2PTGS2
SCHEMBL6942285 0.78 AHR (1.00) AHRLMNACYP2A6CYP1A2CYP3A4
SCHEMBL4456555 0.78 AHR (0.71) AHRCYP3A4MAPK1TP53CYP1B1
SCHEMBL29400074 0.78 AHR (1.00) AHRLMNACYP2A6CYP1A2CYP3A4
SCHEMBL2277002 0.78 AHR (1.00) AHRLMNACYP2A6CYP1A2CYP3A4
SCHEMBL2282125 0.78 AHR (1.00) AHRTP53CYP1B1
SCHEMBL4453342 0.78 CNR2 (0.53) AHRCYP2A6CYP1A2PTGS2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP claimed
CN-119697360-A Resonance frequency detection method and device and electronic equipment 维沃移动通信有限公司 2025-03-25 CN disclosed
CN-119697316-A Motor control method and device and electronic equipment 维沃移动通信有限公司 2025-03-25 CN disclosed
US-20240417573-A1 A METHOD FOR PREPARING AN ANTI-FOULING POLYMERIC COATING MCMASTER UNIVERSITY (CA) 2024-12-19 US disclosed
CN-221487889-U Connection structure of voice coil in loudspeaker 东莞阳康电子有限公司 2024-08-06 CN disclosed
CN-116322562-B Medical/dental handpiece 西亚克特国际有限责任公司 2024-07-16 CN disclosed
CN-220877688-U Riding table 青岛迈金智能科技股份有限公司 2024-05-03 CN disclosed
CN-112930628-B Hybrid electrical connector for high frequency signals 申泰公司 2024-02-20 CN disclosed
CN-220341498-U Combined antenna device and automatic driving vehicle 北京百度网讯科技有限公司 2024-01-12 CN disclosed
CN-117280464-A Liquid-cooled chip packaging structure, printed circuit board assembly and method, and electronic device 华为技术有限公司 2023-12-22 CN disclosed
CN-114077251-A Timing system for robot maze 展讯通信(天津)有限公司 2022-02-22 CN disclosed
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP disclosed
US-20170001052-A1 METHOD FOR ACTIVATING OXYGENASE-CONTAINING COMPOSITION AND CONTAMINANT DETOXIFICATION METHOD AND DEVICE BASED ON SAME TAKAHATA ELECTRONICS CORPORATION (JP) 2017-01-05 US disclosed
US-20120231972-A1 Probe Compound for Detecting and Isolating Enzymes and Means and Methods Using the Same INSTITUTE OF CATALYSIS (CSIC) (ES) 2012-09-13 US disclosed
US-7996156-B2 Methods for predicting properties of molecules THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2011-08-09 US disclosed
WO-2010105851-A1 PROBE COMPOUND FOR DETECTING AND ISOLATING ENZYMES AND MEANS AND METHODS USING THE SAME Helmholtz-Zentrum für Infektionsforschung GmbH (DE) 2010-09-23 WO disclosed
EP-2230312-A1 Probe compound for detecting and isolating enzymes and means and methods using the same Helmholtz-Zentrum für Infektionsforschung GmbH (DE) 2010-09-22 EP disclosed
US-20090269857-A1 Instruments for detecting low-molecular weight substance FUJIKURA KASEI CO., LTD. (JP) 2009-10-29 US disclosed
US-20050148097-A1 Instruments for detecting low-molecular weight substance ENBIOTEC LABORATORIES C., LTD. (JP) 2005-07-07 US disclosed
EP-1489420-A1 INSTRUMENTS FOR DETECTING LOW-MOLECULAR WEIGHT SUBSTANCE Enbiotec Laboratories Co., Ltd. (JP) 2004-12-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120231972-A1 Probe Compound for Detecting and Isolating Enzymes and Means and Methods Using the Same SI, GUSB, MPI AHR 796/4885LMNA 2150/4885CYP2A6 118/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.