SCHEMBL381602

SCHEMBL381602

Clc1ccc(-c2ccccc2)c(Cl)c1Cl

nearest known ligand 0.60

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
AHR P35869 4/20 0.60
CYP2A6 P11509 3/20 0.54
CLCN2 P51788 1/20 0.45
CSNK2A1 P68400 2/20 0.44
CTRC Q99895 2/20 0.42
CYP1A2 P05177 2/20 0.40
BACE1 P56817 1/20 0.39
CYP3A4 P08684 1/20 0.39
MAPK1 P28482 1/20 0.39
ALDH1A1 P00352 1/20 0.38
ALOX5 P09917 1/20 0.38
FEN1 P39748 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29983843 1.00 AHR (0.60) AHRCYP2A6CLCN2CSNK2A1CTRC
Water SCHEMBL7043753 0.98 AHR (0.58) AHRCYP2A6CLCN2CSNK2A1CTRC
Biphenyl SCHEMBL10457114 0.89 CYP2A6 (0.56) AHRCYP2A6CLCN2CSNK2A1CYP1A2
SCHEMBL6005208 0.83 CYP2A6 (0.46) AHRCYP2A6CLCN2CSNK2A1CTRC
SCHEMBL1696360 0.81 CYP2A6 (0.50) AHRCYP2A6CLCN2CSNK2A1CTRC
SCHEMBL2879306 0.81 CYP2A6 (0.50) AHRCYP2A6CLCN2CSNK2A1CTRC
SCHEMBL2288747 0.80 AHR (0.64) AHRCYP2A6CYP1A2CYP3A4MAPK1
SCHEMBL29489437 0.80 CYP2A6 (0.68) CYP2A6MAPK1ALDH1A1
SCHEMBL1250242 0.80 CYP2A6 (0.68) CYP2A6MAPK1ALDH1A1
SCHEMBL932320 0.79 CYP2A6 (0.48) AHRCYP2A6CLCN2CSNK2A1CTRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 598 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119361834-A Electrolyte and battery and electricity utilization device containing same 浙江大学 2025-01-24 CN claimed
CN-118639436-A Evaporation-driven power generation fabric and preparation method thereof 武汉纺织大学 2024-09-13 CN claimed
CN-114814013-B Method for rapidly screening unknown chemical hazard residues in aquatic products based on high-resolution mass spectrum database 中国海洋大学 2023-06-02 CN claimed
CN-218274022-U Soft shielding type automotive wiring harness 徐州市银铃新能源科技有限公司 2023-01-10 CN claimed
CN-111308003-B Method for simultaneously detecting diisopropylnaphthalenes, polychlorinated biphenyls, phthalate compounds and photoinitiator 福建中烟工业有限责任公司 2022-11-08 CN claimed
CN-111665313-B Method for determining polychlorinated biphenyl compounds in aquatic products 孟祥龙 2022-10-11 CN claimed
CN-114874254-A Method for removing trace phenyltrichloro in methyl phenyl dichlorosilane 熵联节能科技(江苏)有限公司 2022-08-09 CN claimed
CN-217010624-U Liquid-cooled motor and vehicle 江苏爱玛车业科技有限公司 2022-07-19 CN claimed
CN-114196618-A Exposure system of organic flame retardant to human respiratory tract cells and preparation method and application thereof 广东工业大学 2022-03-18 CN claimed
CN-109762776-B Microbial agent for improving soil quality, preparation method and application 中国环境科学研究院 2022-02-01 CN claimed
US-6380454-B1 DISTILLATION; SUPPLYING SODIUM; DECHLORINATION BY SALT FORMATION CANADIAN IMPERIAL BANK OF COMMERCE (CA) 2002-04-30 US claimed
EP-1005881-A1 Method and apparatus for decomposing halogenated aliphatic hydrocarbon compounds or aromatic compounds CANON KABUSHIKI KAISHA (JP) 2000-06-07 EP claimed
CN-1245080-A Process for decomposing halogen ester group hydrocarbon compound or aromatic compound and device thereof and process for purifying waste gas and device for this method CANON KK (JP) 2000-02-23 CN claimed
EP-0968739-A1 Method and apparatus for decomposing halogenated aliphatic and aromatic compounds CANON KABUSHIKI KAISHA (JP) 2000-01-05 EP claimed
EP-0503831-B1 Destruction of polychlorinated biphenyls ONTARIO HYDRO (CA) 1997-09-17 EP claimed
EP-0503831-A1 Destruction of polychlorinated biphenyls ONTARIO HYDRO (CA) 1992-09-16 EP claimed
US-4490266-A Process for the preparation of liquids of low inflammability and high viscosity index and the use thereof BAYER AKTIENGESELLSCHAFT (DE) 1984-12-25 US claimed
US-4357213-A Method of recovery of liquid chlorine derivatives of hydrocarbons MANTULO ALEXANDR P 1982-11-02 US claimed
US-4236973-A BY PASSING A CURRENT OF VAPOR THROUGH A MOVING STREAM TO VAPORIZE ANY ORGANICS THE DOW CHEMICAL COMPANY (US) 1980-12-02 US claimed
US-4200698-A BROMO BUTADIENE POLYMER, CHLOROCARBON, EPOXIDIZED CYCLOOLEFIN, POLYAMINE OR POLYAMIDE MICAFIL, AG (CH) 1980-04-29 US claimed