SCHEMBL22889396

SCHEMBL22889396

c1ccc(-c2ccc(-c3nc(-c4cccc(-c5ccccc5)c4)nc(-c4cccc5c4oc4ccccc45)n3)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.50
MAPT P10636 6/20 0.43
ALDH1A1 P00352 4/20 0.42
KDM4E B2RXH2 3/20 0.42
POLB P06746 2/20 0.42
PLA2G2A P14555 3/20 0.42
PLA2G4A P47712 3/20 0.42
NPSR1 Q6W5P4 1/20 0.41
GGPS1 O95749 1/20 0.40
TSHR P16473 4/20 0.39
HPGD P15428 2/20 0.39
PLA2G10 O15496 1/20 0.39
LMNA P02545 3/20 0.39
HSD17B10 Q99714 3/20 0.39
MAPK1 P28482 2/20 0.39
PIM1 P11309 1/20 0.39
CSNK2A2 P19784 1/20 0.39
CSNK2B P67870 1/20 0.39
PIM3 Q86V86 1/20 0.39
PIM2 Q9P1W9 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17425612 1.00 ALOX5 (0.50) ALOX5MAPTALDH1A1KDM4EPOLB
SCHEMBL22888977 1.00 ALOX5 (0.50) ALOX5MAPTALDH1A1KDM4EPOLB
SCHEMBL30022465 1.00 ALOX5 (0.50) ALOX5MAPTALDH1A1KDM4EPOLB
SCHEMBL22889097 1.00 ALOX5 (0.50) ALOX5MAPTALDH1A1KDM4EPOLB
SCHEMBL22889410 1.00 ALOX5 (0.50) ALOX5MAPTALDH1A1KDM4EPOLB
SCHEMBL17425479 1.00 ALOX5 (0.50) ALOX5MAPTALDH1A1KDM4EPOLB
SCHEMBL22889447 1.00 ALOX5 (0.50) ALOX5MAPTALDH1A1KDM4EPOLB
SCHEMBL21304536 1.00 ALOX5 (0.50) ALOX5MAPTALDH1A1KDM4EPOLB
SCHEMBL22889441 0.99 ALOX5 (0.49) ALOX5MAPTALDH1A1KDM4EPOLB
SCHEMBL21304228 0.99 ALOX5 (0.48) ALOX5MAPTALDH1A1KDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024143905-A1 ORGANIC ELECTRIC ELEMENT USING ORGANIC ELECTRIC ELEMENT COMPOUND, AND ELECTRONIC DEVICE 덕산네오룩스 주식회사 2024-07-04 WO disclosed
US-20230309394-A1 ORGANIC ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-09-28 US disclosed
US-20230309394-A1 ORGANIC ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-09-28 US disclosed
US-11765972-B2 Compound and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2023-09-19 US disclosed
US-11765972-B2 Compound and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2023-09-19 US disclosed
US-20230165145-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME AND COMPOSITION FOR ORGANIC MATERIAL LAYER OF ORGANIC LIGHT EMITTING DEVICE LT MATERIALS CO., LTD. (KR) 2023-05-25 US disclosed
US-20210009527-A1 COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO.,LTD. (JP) 2021-01-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210009527-A1 COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME OR10J3, RPS4Y1, AR ALOX5 3163/4885MAPT 2178/4885ALDH1A1 1387/4885
US-11765972-B2 Compound and organic electroluminescence device using the same AR, OR10J3, RPS4Y1 ALOX5 3071/4885MAPT 2233/4885ALDH1A1 1441/4885
US-20230165145-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME AND COMPOSITION FOR ORGANIC MATERIAL LAYER OF ORGANIC LIGHT EMITTING DEVICE CRY1, CYP1A1, CYP1B1 ALOX5 519/4885MAPT 700/4885ALDH1A1 22/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.