Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.45 |
| ▸ | HRH2 | P25021 | 3/20 | 0.45 |
| ▸ | HRH1 | P35367 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22861398 | 1.00 | HTR1A (0.51) | HTR1AHRH3HRH2HRH1KDM4E | |
| SCHEMBL13542804 | 0.91 | HRH3 (0.46) | HTR1AHRH3HRH2HRH1 | |
| SCHEMBL13543540 | 0.91 | HRH3 (0.46) | HTR1AHRH3HRH2HRH1 | |
| SCHEMBL22281966 | 0.87 | HTR1A (0.54) | HTR1AHRH3HRH2HRH1KDM4E | |
| SCHEMBL20729452 | 0.87 | HTR1A (0.54) | HTR1AHRH3HRH2HRH1KDM4E | |
| SCHEMBL20729427 | 0.87 | HTR1A (0.54) | HTR1AHRH3HRH2HRH1KDM4E | |
| SCHEMBL21376977 | 0.85 | GLB1 (0.38) | HTR1AHRH3HRH2HRH1 | |
| SCHEMBL22890929 | 0.82 | HRH3 (0.41) | HRH3HRH2HRH1ALDH1A1MAOB | |
| SCHEMBL27447200 | 0.81 | HTR1A (0.49) | HTR1AHRH3HRH2HRH1BCHE | |
| SCHEMBL24497793 | 0.81 | HTR1A (0.49) | HTR1AHRH3HRH2HRH1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11702429-B2 | mTORC modulators and uses thereof | AEOVIAN PHARMACEUTICALS, INC. (US) | 2023-07-18 | — | — | US | disclosed |
| US-20230013344-A1 | MTORC MODULATORS AND USES THEREOF | EVOTEC (FRANCE) SAS (FR) | 2023-01-19 | — | — | US | disclosed |
| US-11230557-B2 | mTORC modulators and uses thereof | AEOVIAN PHARMACEUTICALS, INC. (US) | 2022-01-25 | — | — | US | disclosed |
| US-20210008041-A1 | MTORC MODULATORS AND USES THEREOF | AEOVIAN PHARMACEUTICALS, INC. | 2021-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11702429-B2 | mTORC modulators and uses thereof | MTOR, RICTOR, RPTOR | HTR1A 4040/4885HRH3 3363/4885HRH2 3574/4885 |
| US-20210008041-A1 | MTORC MODULATORS AND USES THEREOF | MTOR, RICTOR, RPTOR | HTR1A 4040/4885HRH3 3363/4885HRH2 3574/4885 |
| US-11230557-B2 | mTORC modulators and uses thereof | MTOR, RICTOR, RPTOR | HTR1A 4040/4885HRH3 3363/4885HRH2 3574/4885 |
| US-20230013344-A1 | MTORC MODULATORS AND USES THEREOF | MTOR, RICTOR, RPTOR | HTR1A 4040/4885HRH3 3363/4885HRH2 3574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.