Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 13/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20729452 | 0.94 | HTR1A (0.54) | HTR1AHRH3HRH2HRH1 | |
| SCHEMBL22281966 | 0.94 | HTR1A (0.54) | HTR1AHRH3HRH2HRH1 | |
| SCHEMBL20729427 | 0.94 | HTR1A (0.54) | HTR1AHRH3HRH2HRH1 | |
| SCHEMBL9917377 | 0.84 | HRH3 (0.49) | HTR1AHRH3HRH2HRH1 | |
| SCHEMBL9917378 | 0.84 | HRH3 (0.49) | HTR1AHRH3HRH2HRH1 | |
| SCHEMBL21667892 | 0.84 | HRH3 (0.49) | HTR1AHRH3HRH2HRH1 | |
| SCHEMBL27359356 | 0.81 | MAOB (0.44) | HRH3HRH2HRH1SIGMAR1 | |
| SCHEMBL22861398 | 0.81 | HTR1A (0.51) | HTR1AHRH3HRH2HRH1BCHE | |
| SCHEMBL22890922 | 0.81 | HTR1A (0.51) | HTR1AHRH3HRH2HRH1BCHE | |
| SCHEMBL24925644 | 0.80 | HTR1A (0.43) | HTR1AHRH3HRH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1058399-A | New piperidine ether and thioether as cholesteral biosynthesis inhibitor | MERRELL DOW PHARMA (US) | 1992-02-05 | — | — | CN | disclosed |