Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 4/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1274286 | 0.89 | ALDH1A1 (0.55) | MEN1KMT2AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL11030544 | 0.84 | BRD4 (0.46) | MEN1KMT2AALDH1A1ACHEMAPT | |
| SCHEMBL22815495 | 0.84 | MEN1 (0.41) | MEN1KMT2AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL25307258 | 0.83 | EGFR (0.42) | MEN1KMT2AALDH1A1ACHEEGFR | |
| SCHEMBL30550465 | 0.83 | EGFR (0.42) | MEN1KMT2AALDH1A1ACHEEGFR | |
| SCHEMBL21052196 | 0.81 | PTGS2 (0.53) | MEN1KMT2AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL21098689 | 0.81 | EGFR (0.41) | MEN1KMT2AALDH1A1EGFRNFE2L2 | |
| SCHEMBL15898570 | 0.81 | ALDH1A1 (0.42) | MEN1KMT2AALDH1A1CYP1A2MAPT | |
| SCHEMBL24755482 | 0.81 | EGFR (0.41) | MEN1KMT2AALDH1A1EGFRNFE2L2 | |
| SCHEMBL7340707 | 0.81 | KDM4E (0.54) | ALDH1A1ACHEMAPTEGFRELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111909083-B | Inhibitors of histone demethylase | 赛尔基因昆蒂赛尔研究公司 | 2023-08-15 | — | — | CN | disclosed |
| EP-3160952-B1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2020-12-02 | — | — | EP | disclosed |
| EP-3160952-B1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2020-12-02 | — | — | EP | disclosed |
| EP-3741749-A1 | HISTONE DEMETHYLASE INHIBITORS | Celgene Quanticel Research, Inc. (US) | 2020-11-25 | — | — | EP | disclosed |
| EP-3741749-A1 | HISTONE DEMETHYLASE INHIBITORS | Celgene Quanticel Research, Inc. (US) | 2020-11-25 | — | — | EP | disclosed |
| EP-3738960-A1 | HISTONE DEMETHYLASE INHIBITORS | Celgene Quanticel Research, Inc. (US) | 2020-11-18 | — | — | EP | disclosed |
| EP-3738960-A1 | HISTONE DEMETHYLASE INHIBITORS | Celgene Quanticel Research, Inc. (US) | 2020-11-18 | — | — | EP | disclosed |
| CN-111909083-A | Histone demethylase inhibitors | 赛尔基因昆蒂赛尔研究公司 | 2020-11-10 | — | — | CN | disclosed |
| CN-106660982-B | Histone demethylase inhibitors | 赛尔基因昆蒂赛尔研究公司 | 2020-09-08 | — | — | CN | disclosed |
| US-10385047-B2 | Histone demethylase inhibitors | CELGENE QUANTICEL RESEARCH, INC. (US) | 2019-08-20 | — | — | US | disclosed |
| US-4310669-A | TETRALONE | PFIZER INC. (US) | 1982-01-12 | — | — | US | disclosed |
| US-4310668-A | Intermediates to 1,9-dihydroxyoctahydrophenanthrenes | PFIZER INC. (US) | 1982-01-12 | — | — | US | disclosed |
| US-4270005-A | ANALGESICS | PFIZER INC. (US) | 1981-05-26 | — | — | US | disclosed |
| US-4268523-A | ANALGESICS | PFIZER INC. (US) | 1981-05-19 | — | — | US | disclosed |
| US-4268692-A | ANALGESICS | PFIZER INC. (US) | 1981-05-19 | — | — | US | disclosed |
| US-4237133-A | ANALGESICS | PFIZER INC. (US) | 1980-12-02 | — | — | US | disclosed |
| US-4188495-A | 1,9-Dihydroxyoctahydrophenanthrenes and intermediates therefor | PFIZER INC. (US) | 1980-02-12 | — | — | US | disclosed |
| US-4169108-A | 5(OR 6)-[(Substituted-amino)alkyl]-2,3-naphthalenediols | STERLING DRUG INC. (US) | 1979-09-25 | — | — | US | disclosed |
| US-3951959-A | VAGINOTROPIC | SCHERING AKTIENGESELLSCHAFT (DT) | 1976-04-20 | — | — | US | disclosed |
| US-3951958-A | VAGINOTROPIC | SCHERING AKTIENGESELLSCHAFT (DT) | 1976-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10385047-B2 | Histone demethylase inhibitors | KDM1B, KDM6A, KDM1A | MEN1 3059/4885KMT2A 47/4885ALDH1A1 475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.