SCHEMBL2289235

SCHEMBL2289235

CNc1ccccc1/C=C/C=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK4 P11802 4/20 0.52
CCND1 P24385 4/20 0.52
ALDH1A1 P00352 6/20 0.43
LMNA P02545 2/20 0.43
MAPK1 P28482 2/20 0.43
TRPA1 O75762 1/20 0.43
ALOX5 P09917 1/20 0.43
CCNB2 O95067 2/20 0.42
CDK1 P06493 2/20 0.42
CCNB1 P14635 2/20 0.42
CCNB3 Q8WWL7 2/20 0.42
MAPT P10636 5/20 0.39
KDM4E B2RXH2 4/20 0.39
POLB P06746 3/20 0.39
RECQL P46063 3/20 0.39
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
HPGD P15428 2/20 0.39
HTT P42858 1/20 0.39
TDP1 Q9NUW8 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2614337 1.00 CDK4 (0.52) CDK4CCND1ALDH1A1LMNAMAPK1
SCHEMBL22058627 0.80 TDP1 (0.52) ALDH1A1LMNAMAPK1MAPTKDM4E
SCHEMBL24063595 0.80 POLB (0.38) CDK4CCND1ALDH1A1MAPK1MAPT
SCHEMBL25448951 0.80 KDM4E (0.38) CDK4CCND1ALDH1A1MAPK1MAPT
SCHEMBL20356121 0.80 KDM4E (0.38) CDK4CCND1ALDH1A1MAPK1MAPT
SCHEMBL9391320 0.79 CDK4 (0.47) CDK4CCND1ALDH1A1LMNAMAPK1
SCHEMBL874034 0.79 TDP1 (0.55) ALDH1A1LMNAMAPK1MAPTKDM4E
SCHEMBL5555577 0.78 CYP2C19 (0.55) CDK4CCND1ALDH1A1MAPK1MAPT
SCHEMBL5555579 0.78 CYP2C19 (0.55) CDK4CCND1ALDH1A1MAPK1MAPT
SCHEMBL16476616 0.78 CDK4 (0.70) CDK4CCND1ALDH1A1LMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7994099-B2 Corrosion inhibitor compositions comprising an aldehyde and a thiol and/or an amine functionalized ring structure and associated methods HALIBURTON ENERGY SERVICES, INC. (US) 2011-08-09 US claimed