SCHEMBL25448951

SCHEMBL25448951

C/C=C\C=C\c1ccccc1NC

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.38
POLB P06746 3/20 0.38
MAPT P10636 3/20 0.38
ALDH1A1 P00352 2/20 0.38
HPGD P15428 2/20 0.38
RECQL P46063 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
USP2 O75604 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
HSD17B10 Q99714 1/20 0.38
MEN1 O00255 1/20 0.36
HTT P42858 1/20 0.36
KMT2A Q03164 1/20 0.36
ATM Q13315 1/20 0.32
APP P05067 1/20 0.32
EGFR P00533 1/20 0.32
PABPC1 P11940 1/20 0.32
MAPK1 P28482 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20356121 1.00 KDM4E (0.38) KDM4EPOLBMAPTALDH1A1HPGD
SCHEMBL12872100 0.85 KDM4E (0.41) KDM4EPOLBMAPTALDH1A1HPGD
SCHEMBL16424666 0.85 KDM4E (0.41) KDM4EPOLBMAPTALDH1A1HPGD
SCHEMBL21547202 0.81 KDM4E (0.35) KDM4EPOLBMAPTALDH1A1HPGD
SCHEMBL18287111 0.81 KDM4E (0.35) KDM4EPOLBMAPTALDH1A1HPGD
SCHEMBL2289235 0.80 CDK4 (0.52) KDM4EPOLBMAPTALDH1A1HPGD
SCHEMBL2614337 0.80 CDK4 (0.52) KDM4EPOLBMAPTALDH1A1HPGD
SCHEMBL24063595 0.80 POLB (0.38) KDM4EPOLBMAPTALDH1A1HPGD
SCHEMBL25672667 0.78 ALDH1A1 (0.33) ALDH1A1RECQLSMN1; SMN2CDK4CCND1
SCHEMBL24161839 0.77 CYP3A4 (0.36) KDM4EMAPTALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230172044-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE HAVING THEREOF LG DISPLAY CO., LTD. (KR) 2023-06-01 US disclosed
US-20230172050-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE HAVING THEREOF LG DISPLAY CO., LTD. (KR) 2023-06-01 US disclosed
US-20230171979-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE HAVING THEREOF LG DISPLAY CO., LTD. (KR) 2023-06-01 US disclosed
US-20230142498-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230142498-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, LEF1 KDM4E 3601/4885POLB 433/4885MAPT 3520/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.