Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.44 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22058627 | 0.87 | TDP1 (0.52) | TDP1LMNAKMT2AMEN1THRB | |
| SCHEMBL23876405 | 0.83 | TDP1 (0.46) | TDP1LMNAKMT2AMEN1THRB | |
| SCHEMBL28333503 | 0.82 | LMNA (0.50) | TDP1LMNAKMT2AMEN1THRB | |
| SCHEMBL16470058 | 0.80 | TDP1 (0.42) | TDP1LMNAKMT2AMEN1THRB | |
| SCHEMBL4333864 | 0.80 | LMNA (0.60) | TDP1LMNAKMT2AMEN1THRB | |
| SCHEMBL2495661 | 0.80 | POLB (0.46) | TDP1LMNAKMT2AMEN1THRB | |
| SCHEMBL21022106 | 0.79 | ERN1 (0.42) | TDP1LMNAKMT2AMEN1THRB | |
| SCHEMBL21639549 | 0.79 | TDP1 (0.41) | TDP1LMNAKMT2AMEN1THRB | |
| SCHEMBL2614337 | 0.79 | CDK4 (0.52) | TDP1LMNAKMT2AMEN1THRB | |
| SCHEMBL2289235 | 0.79 | CDK4 (0.52) | TDP1LMNAKMT2AMEN1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 223 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113288897-B | Application of neobynine derivatives in preparation of drugs for treating gastric cancer | 兰州大学 | 2022-05-27 | — | — | CN | claimed |
| CN-113288897-A | Application of neobynine derivatives in preparation of drugs for treating gastric cancer | 兰州大学 | 2021-08-24 | — | — | CN | claimed |
| CN-110669058-A | Tricyclic quinolone carboxylic acid and preparation method thereof | 江西农业大学 | 2020-01-10 | — | — | CN | claimed |
| CN-106622244-B | A kind of method nitrogen-doped carbon material package Co catalysts and prepare secondary-amine compound using it | 中南民族大学 | 2019-06-14 | — | — | CN | claimed |
| CN-109288860-A | A kind of application of the gold nano grain of Aminylferrocene class molecular compound modification in pharmacy | 山东大学 | 2019-02-01 | — | — | CN | claimed |
| CN-106622244-A | Nitrogen-doped carbon material encapsulated cobalt catalyst and method of using the catalyst to prepare secondary amine compounds | 中南民族大学 | 2017-05-10 | — | — | CN | claimed |
| CN-104119285-B | Compound and application thereof as estrogen-related receptor modulator | 中国科学院广州生物医药与健康研究院 | 2016-06-29 | — | — | CN | claimed |
| CN-104119285-A | Compound used as estrogen-related receptor regulator and application of compound | GUANGZHOU INST BIOMED & HEALTH | 2014-10-29 | — | — | CN | claimed |
| JP-4794856-B2 | — | — | 2011-10-19 | — | — | JP | claimed |
| US-20100120044-A1 | MODIFIED POLYNUCLEOTIDES COMPRISING RIBOSE RINGS | QIAGEN GMBH (DE) | 2010-05-13 | — | — | US | claimed |
| EP-1196631-A1 | POLYNUCLEOTIDES | Cyclops Genome Sciences Limited (GB) | 2002-04-17 | — | — | EP | claimed |
| WO-2002016381-A2 | COMPOSITION AND METHOD FOR INHIBITING PLATELET AGGREGATION | INSPIRE PHARMACEUTICALS, INC. (US) | 2002-02-28 | — | — | WO | claimed |
| WO-2001094626-A1 | POLYNUCLEOTIDES | CYCLOPS GENOME SCIENCES LIMITED (GB) | 2001-12-13 | — | — | WO | claimed |
| EP-1107758-A2 | USE OF PIPERIDINES AND/OR PIPERAZINES AS INHIBITORS OF P38-ALPHA KINASE | SCIOS INC. (US) | 2001-06-20 | — | — | EP | claimed |
| WO-2000075306-A2 | METHOD FOR PRODUCING DOUBLE STRANDED POLYNUCLEOTIDES | CYCLOPS GENOME SCIENCES LIMITED (GB) | 2000-12-14 | — | — | WO | claimed |
| WO-2000066605-A2 | POLYNUCLEOTIDES | CYCLOPS GENOME SCIENCES LIMITED (GB) | 2000-11-09 | — | — | WO | claimed |
| EP-1001943-A1 | POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | Aventis Pharma S.A. (FR) | 2000-05-24 | — | — | EP | claimed |
| WO-2000012074-A2 | USE OF PIPERIDINES AND/OR PIPERAZINES AS INHIBITORS OF P38-ALPHA KINASE | SCIOS INC. (US) | 2000-03-09 | — | — | WO | claimed |
| WO-1999003843-A1 | POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | RHONE-POULENC RORER S.A. (FR) | 1999-01-28 | — | — | WO | claimed |
| WO-1999001607-A2 | ENZYMATIC OXIDATION SYSTEM WITH NOVEL ENZYMATIC-EFFECT ENHANCING COMPOUNDS | CALL, KRIMHILD (DE) | 1999-01-14 | — | — | WO | claimed |