SCHEMBL22894337

SCHEMBL22894337

Cc1ccc(NCCc2ccc(Cl)cc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.65
CNR1 P21554 3/20 0.60
TAAR1 Q96RJ0 1/20 0.55
GPR84 Q9NQS5 2/20 0.50
GALR3 O60755 1/20 0.48
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
LMNA P02545 2/20 0.47
POLB P06746 1/20 0.47
TP53 P04637 3/20 0.46
KMT2A Q03164 2/20 0.46
MEN1 O00255 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22894161 0.89 CHRM1 (0.56) MAPTCNR1TAAR1NPC1RAB9A
SCHEMBL11526668 0.86 MAPT (0.77) MAPTCNR1NPC1RAB9ALMNA
SCHEMBL26267972 0.85 TAAR1 (0.60) MAPTCNR1TAAR1GPR84RAB9A
SCHEMBL27724007 0.83 MAPT (0.67) MAPTCNR1GPR84NPC1RAB9A
SCHEMBL26267723 0.83 MAPT (0.67) MAPTCNR1TAAR1GPR84GALR3
SCHEMBL24756902 0.81 MAPT (0.65) MAPTCNR1TAAR1GPR84GALR3
SCHEMBL26267841 0.81 MAPT (0.65) MAPTCNR1TAAR1GPR84GALR3
SCHEMBL28625506 0.81 MAPT (0.57) MAPTCNR1TAAR1GPR84NPC1
SCHEMBL3904496 0.81 L3MBTL1 (0.70) MAPTTAAR1NPC1RAB9AKMT2A
SCHEMBL248884 0.81 L3MBTL1 (0.70) MAPTTAAR1GPR84NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11696937-B2 Glycopeptide compounds having activity of resisting drug-resistant bacteria, and preparation method and application thereof SHANGHAI LAIYI CENTER FOR BIOPHARMACEUTICAL R&D CO., LTD. (CN) 2023-07-11 US disclosed
US-11696937-B2 Glycopeptide compounds having activity of resisting drug-resistant bacteria, and preparation method and application thereof SHANGHAI LAIYI CENTER FOR BIOPHARMACEUTICAL R&D CO., LTD. (CN) 2023-07-11 US disclosed
US-20210093691-A1 Glycopeptide Compounds Having Activity Of Resisting Drug-Resistant Bacteria, And Preparation Method And Application Thereof SHANGHAI LAIYI CENTER FOR BIOPHARMACEUTICAL R&D CO., LTD. (CN) 2021-04-01 US disclosed
EP-3763728-A1 GLYCOPEPTIDE COMPOUNDS HAVING ACTIVITY OF RESISTING DRUG-RESISTANT BACTERIA, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF Shanghai LaiYi Center For Biopharmaceutical R&D Co., Ltd. (CN) 2021-01-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210093691-A1 Glycopeptide Compounds Having Activity Of Resisting Drug-Resistant Bacteria, And Preparation Method And Application Thereof VIP, CUTA, MGAM MAPT 3389/4885CNR1 4714/4885TAAR1 3759/4885
US-11696937-B2 Glycopeptide compounds having activity of resisting drug-resistant bacteria, and preparation method and application thereof VIP, CUTA, MGAM MAPT 3389/4885CNR1 4714/4885TAAR1 3759/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.