Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 2/20 | 0.62 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.62 |
| ▸ | BTK | Q06187 | 2/20 | 0.53 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | MERTK | Q12866 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23292251 | 1.00 | CCNK (0.62) | CCNKCDK12BTKHRH4GPR119 | |
| SCHEMBL28545656 | 0.85 | CCNK (0.66) | CCNKCDK12HRH4JAK2FLT3 | |
| SCHEMBL28545658 | 0.85 | CCNK (0.66) | CCNKCDK12HRH4JAK2FLT3 | |
| SCHEMBL22895718 | 0.82 | CDK12 (0.60) | CCNKCDK12BTKGPR119USP30 | |
| SCHEMBL28544845 | 0.82 | CDK12 (0.60) | CCNKCDK12BTKGPR119USP30 | |
| SCHEMBL23292284 | 0.82 | CDK12 (0.60) | CCNKCDK12BTKGPR119USP30 | |
| SCHEMBL22895525 | 0.79 | CDK12 (0.60) | CCNKCDK12BTKGPR119USP30 | |
| SCHEMBL23292355 | 0.79 | CDK12 (0.60) | CCNKCDK12BTKGPR119USP30 | |
| SCHEMBL28550665 | 0.79 | CDK12 (0.60) | CCNKCDK12BTKGPR119USP30 | |
| SCHEMBL5097018 | 0.79 | MAPK10 (0.64) | BTKUSP30MAPK8MAPK9MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11358958-B2 | — | — | 2022-06-14 | — | — | US | disclosed |
| US-20210130340-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASES | KINNATE BIOPHARMA INC. | 2021-05-06 | — | — | US | disclosed |
| US-10894788-B2 | Inhibitors of cyclin-dependent kinases | KINNATE BIOPHARMA INC. (US) | 2021-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11358958-B2 | — | CDK2, CDK1, CDK6 | CCNK 7/4885CDK12 19/4885BTK 852/4885 |
| US-20210130340-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASES | CDK2, CCNK, CDK1 | CCNK 2/4885CDK12 22/4885BTK 724/4885 |
| US-10894788-B2 | Inhibitors of cyclin-dependent kinases | CDK2, CCNK, CDK1 | CCNK 2/4885CDK12 22/4885BTK 724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.