⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17071965 | 0.77 | — | — | |
| SCHEMBL4633374 | 0.72 | — | — | |
| SCHEMBL24278796 | 0.67 | HSD11B1 (0.33) | — | |
| SCHEMBL25796571 | 0.67 | HSD11B1 (0.33) | — | |
| SCHEMBL24282190 | 0.67 | HSD11B1 (0.33) | — | |
| SCHEMBL241062 | 0.67 | — | — | |
| SCHEMBL11539159 | 0.67 | MAPT (0.34) | — | |
| SCHEMBL11950291 | 0.66 | CYP2C9 (0.32) | — | |
| SCHEMBL5954896 | 0.65 | — | — | |
| SCHEMBL13631509 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110319446-A1 | BICYCLO[2.2.1]HEPT-7-YLAMINE DERIVATIVES AND THEIR USES | ARGENTA DISCOVERY LTD. (GB) | 2011-12-29 | — | — | US | disclosed |
| US-7994211-B2 | Bicyclo[2.2.1]hept-7-ylamine derivatives and their uses | ARGENTA DISCOVERY LIMITED (GB) | 2011-08-09 | — | — | US | disclosed |
| US-20100144852-A1 | Bicyclo[2.2.1]hept-7-ylamine Derivatives and Their Uses | ARGENTA DISCOVERY LIMITED (GB) | 2010-06-10 | — | — | US | disclosed |
| EP-1924553-A1 | BICYCLO[2.2.]HEPT-7-YLAMINE DERIVATIVES AND THEIR USES | Argenta Discovery Limited (GB) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007017670-A1 | BICYCLO[2.2.]HEPT-7-YLAMINE DERIVATIVES AND THEIR USES | ARGENTA DISCOVERY LTD. (GB) | 2007-02-15 | — | — | WO | disclosed |