Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ITGAL | P20701 | 14/20 | 0.47 |
| ▸ | ITGB2 | P05107 | 13/20 | 0.46 |
| ▸ | ICAM1 | P05362 | 13/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22898603 | 0.76 | ITGAL (0.41) | MEN1KMT2AITGALITGB2ICAM1 | |
| SCHEMBL11762036 | 0.74 | TSHR (0.47) | RAB9AMEN1KMT2A | |
| SCHEMBL22898559 | 0.73 | ITGAL (0.41) | MEN1KMT2AITGALITGB2ICAM1 | |
| SCHEMBL4692248 | 0.71 | ALOX5 (0.47) | ITGALITGB2ICAM1 | |
| SCHEMBL17347096 | 0.69 | ITGAL (0.42) | MEN1KMT2AITGALITGB2ICAM1 | |
| SCHEMBL17338997 | 0.69 | ITGAL (0.42) | MEN1KMT2AITGALITGB2ICAM1 | |
| SCHEMBL17338998 | 0.69 | ITGAL (0.42) | MEN1KMT2AITGALITGB2ICAM1 | |
| SCHEMBL17338995 | 0.69 | ITGAL (0.42) | MEN1KMT2AITGALITGB2ICAM1 | |
| SCHEMBL17347061 | 0.69 | ITGAL (0.42) | MEN1KMT2AITGALITGB2ICAM1 | |
| SCHEMBL18787390 | 0.69 | ITGAL (0.42) | MEN1KMT2AITGALITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3154941-B1 | SMALL MOLECULE LFA-1 INHIBITORS | ALLOCYTE PHARMACEUTICALS AG (CH) | 2021-01-20 | — | — | EP | disclosed |