SCHEMBL22899342

SCHEMBL22899342

CC1=CC(C)CC=C1c1ccccc1N

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
HSD17B10 Q99714 2/20 0.34
GAA P10253 2/20 0.33
KDM4E B2RXH2 1/20 0.33
NPC1 O15118 1/20 0.33
CYP3A4 P08684 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
NOS3 P29474 1/20 0.30
NOS2 P35228 1/20 0.30
MEN1 O00255 1/20 0.30
USP2 O75604 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20860414 0.74 ALDH1A1 (0.36) ALDH1A1L3MBTL1HSD17B10GAAKDM4E
SCHEMBL22298316 0.73 ALDH1A1 (0.46) ALDH1A1L3MBTL1HSD17B10GAAKDM4E
SCHEMBL23766466 0.72 CYP3A4 (0.34) ALDH1A1HSD17B10CYP3A4TDP1
SCHEMBL21698480 0.71 ALDH1A1 (0.41) ALDH1A1HSD17B10KDM4ENPC1CYP3A4
SCHEMBL22562268 0.70 ALDH1A1 (0.39) ALDH1A1L3MBTL1HSD17B10GAAKDM4E
SCHEMBL20860413 0.68 ALDH1A1 (0.40) ALDH1A1L3MBTL1HSD17B10GAAKDM4E
SCHEMBL22780700 0.68 ALDH1A1 (0.40) ALDH1A1L3MBTL1HSD17B10GAAKDM4E
SCHEMBL20629280 0.68 ALDH1A1 (0.40) ALDH1A1L3MBTL1HSD17B10GAAKDM4E
SCHEMBL21782896 0.68
SCHEMBL21650444 0.67 NOS1 (0.33) HSD17B10CYP3A4TDP1NOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3461830-B1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE ORGANOMETALLIC COMPOUND, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND SAMSUNG ELECTRONICS CO LTD (KR) 2021-01-20 EP disclosed