Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | USP2 | O75604 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.63 |
| ▸ | SLC10A2 | Q12908 | 2/20 | 0.63 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.63 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.63 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.63 |
| ▸ | CA1 | P00915 | 7/20 | 0.56 |
| ▸ | CA2 | P00918 | 7/20 | 0.56 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | VDR | P11473 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.51 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8736941 | 0.91 | MAPT (0.81) | MAPTMEN1KMT2AUSP2LMNA | |
| SCHEMBL133225 | 0.91 | MAPT (0.81) | MAPTMEN1KMT2AUSP2LMNA | |
| SCHEMBL14188114 | 0.90 | MAPT (0.83) | MAPTMEN1KMT2AUSP2LMNA | |
| SCHEMBL13014309 | 0.90 | MAPT (0.83) | MAPTMEN1KMT2AUSP2LMNA | |
| SCHEMBL5031235 | 0.90 | MAPT (0.83) | MAPTMEN1KMT2AUSP2LMNA | |
| SCHEMBL5032855 | 0.90 | MAPT (0.83) | MAPTMEN1KMT2AUSP2LMNA | |
| SCHEMBL20079324 | 0.90 | MAPT (0.83) | MAPTMEN1KMT2AUSP2LMNA | |
| SCHEMBL14570878 | 0.90 | MAPT (0.83) | MAPTMEN1KMT2AUSP2LMNA | |
| SCHEMBL15289542 | 0.90 | MAPT (0.83) | MAPTMEN1KMT2AUSP2LMNA | |
| SCHEMBL19313971 | 0.90 | MAPT (0.83) | MAPTMEN1KMT2AUSP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989417-B2 | Linkers for radiopharmaceutical compounds | BRACCO IMAGING S.P.A. (IT) | 2011-08-02 | — | — | US | disclosed |
| EP-1583564-B1 | IMPROVED LINKERS FOR RADIOPHARMACEUTICAL COMPOUNDS | BRACCO IMAGING SPA (IT) | 2009-07-01 | — | — | EP | disclosed |
| EP-1583564-A4 | IMPROVED LINKERS FOR RADIOPHARMACEUTICAL COMPOUNDS | BRACCO IMAGING SPA (IT) | 2007-06-13 | — | — | EP | disclosed |
| US-20060241018-A1 | Linkers for radiopharmaceutical compounds | BRACCO IMAGING S.P.A. (IT) | 2006-10-26 | — | — | US | disclosed |
| EP-1583564-A2 | IMPROVED LINKERS FOR PHARMACEUTICAL COMPOUNDS | Bracco Imaging, S.P.A. (IT) | 2005-10-12 | — | — | EP | disclosed |
| WO-2004062574-A9 | IMPROVED LINKERS FOR RADIOPHARMACEUTICAL COMPOUNDS | BRACCO IMAGING SPA (IT) | 2005-05-26 | — | — | WO | disclosed |
| WO-2004062574-A2 | IMPROVED LINKERS FOR RADIOPHARMACEUTICAL COMPOUNDS | BRACCO IMAGING S.P.A. (IT) | 2004-07-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060241018-A1 | Linkers for radiopharmaceutical compounds | VIP, QPCT, NPPA | MAPT 2998/4885MEN1 15/4885KMT2A 1195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.