Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 10/20 | 0.33 |
| ▸ | CA1 | P00915 | 5/20 | 0.32 |
| ▸ | CA12 | O43570 | 4/20 | 0.32 |
| ▸ | CA9 | Q16790 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22899782 | 0.84 | — | — | |
| SCHEMBL29587079 | 0.80 | CA2 (0.31) | CA2 | |
| SCHEMBL22899756 | 0.73 | — | — | |
| SCHEMBL31189109 | 0.71 | CA2 (0.32) | CA2CA1CA12CA9 | |
| SCHEMBL28744206 | 0.69 | CA2 (0.31) | CA2CA1CA12CA9 | |
| SCHEMBL22899810 | 0.68 | NLRP3 (0.53) | CA2 | |
| SCHEMBL22899781 | 0.67 | CA2 (0.30) | CA2CA1CA12CA9 | |
| SCHEMBL22899664 | 0.62 | POLB (0.33) | — | |
| SCHEMBL23844407 | 0.61 | CA2 (0.32) | CA2 | |
| SCHEMBL8317066 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114555569-B | NLRP3 modulators | 祖玛珍生物科学有限公司 | 2024-10-29 | — | — | CN | disclosed |
| CN-114555569-A | NLRP3 modulators | 祖玛珍生物科学有限公司 | 2022-05-27 | — | — | CN | disclosed |
| EP-3999179-A1 | NLRP3 MODULATORS | Zomagen Biosciences Ltd (US) | 2022-05-25 | — | — | EP | disclosed |
| WO-2021009567-A1 | NLRP3 MODULATORS | ZOMAGEN BIOSCIENCES LTD (US) | 2021-01-21 | — | — | WO | disclosed |