Sugi Predict

Sugi Predict / Compounds / SCHEMBL2290004

SCHEMBL2290004

SCHEMBL2290004

COCOc1ccccc1C(=O)OC

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SLC6A3 Q01959 2/20 0.56
▸ HSP90AA1 P07900 2/20 0.54
▸ MAPT P10636 2/20 0.54
▸ HTT P42858 2/20 0.54
▸ NPSR1 Q6W5P4 1/20 0.54
▸ ALDH1A1 P00352 4/20 0.52
▸ TSHR P16473 2/20 0.52
▸ LMNA P02545 1/20 0.52
▸ L3MBTL1 Q9Y468 1/20 0.51
▸ KMT2A Q03164 3/20 0.51
▸ MEN1 O00255 2/20 0.51
▸ GAA P10253 1/20 0.51
▸ CHEK1 O14757 1/20 0.51
▸ AURKA O14965 1/20 0.51
▸ DAPK3 O43293 1/20 0.51
▸ JAK2 O60674 1/20 0.51
▸ ABL1 P00519 1/20 0.51
▸ NTRK1 P04629 1/20 0.51
▸ FYN P06241 1/20 0.51
▸ CSF1R P07333 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14648839 0.86 LMNA (0.58) SLC6A3HSP90AA1MAPTHTTNPSR1
SCHEMBL30070812 0.85 ELANE (0.49) SLC6A3MAPTHTTALDH1A1TSHR
SCHEMBL14330483 0.85 ELANE (0.49) SLC6A3MAPTHTTALDH1A1TSHR
SCHEMBL12417943 0.85 TSHR (0.62) MAPTNPSR1ALDH1A1TSHRLMNA
SCHEMBL31033384 0.85 CHEK1 (0.51) SLC6A3HSP90AA1MAPTHTTNPSR1
SCHEMBL28285304 0.85 CHEK1 (0.51) SLC6A3HSP90AA1MAPTHTTNPSR1
SCHEMBL5838452 0.85 CHEK1 (0.51) SLC6A3HSP90AA1MAPTHTTNPSR1
SCHEMBL385973 0.84 HSP90AA1 (0.59) SLC6A3HSP90AA1MAPTHTTNPSR1
SCHEMBL2290756 0.84 ALDH1A1 (0.61) MAPTHTTNPSR1ALDH1A1TSHR
SCHEMBL1989129 0.84 HCRTR1 (0.65) SLC6A3HSP90AA1MAPTHTTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118290238-A Preparation method of isorhapontin 深圳技术大学 2024-07-05 — — CN claimed
CN-116514759-A Synthesis method of dihydromyricetin 华中农业大学 2023-08-01 — — CN claimed
EP-4631952-A1 GLUCOCORTICOID RECEPTOR AGONIST AND CONJUGATE THEREOF Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) 2025-10-15 — — EP disclosed
WO-2024149093-A1 GLUCOCORTICOID RECEPTOR AGONIST AND CONJUGATE THEREOF 四川科伦博泰生物医药股份有限公司 2024-07-18 — — WO disclosed
CN-118290238-A Preparation method of isorhapontin 深圳技术大学 2024-07-05 — — CN disclosed
CN-116514759-A Synthesis method of dihydromyricetin 华中农业大学 2023-08-01 — — CN disclosed
CN-105408321-A Novel derivatives of indole and pyrrole, method for the production thereof and pharmaceutical compositions containing same SERVIER LAB 2016-03-16 — — CN disclosed
US-7989430-B2 Antibacterial agents REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2011-08-02 — — US disclosed
US-7989430-B2 Antibacterial agents REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2011-08-02 — — US disclosed
US-20080293666-A1 Antibacterial Agents REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2008-11-27 — — US disclosed
US-20080293666-A1 Antibacterial Agents REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2008-11-27 — — US disclosed
WO-2007067559-A2 ANTIBACTERIAL AGENTS REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2007-06-14 — — WO disclosed
EP-0889042-B1 RADICICOL DERIVATIVES KYOWA HAKKO KOGYO KK (JP) 2004-05-06 — — EP disclosed
US-20040053990-A1 Radicicol derivatives KYOWA HAKKO KOGYO CO., LTD (JP) 2004-03-18 — — US disclosed
US-6635662-B2 A 2-oxime derivative; antitumor and -carcinogenic agents; immunosuppressents; osteoporosis; enzyme inhibitors of tyrosine kinase activity KYOWA HAKKO KOGYO CO., LTD. (JP) 2003-10-21 — — US disclosed
US-6316491-B1 INHIBITORS OF TYROSINE KINASE USED AS ANTITUMOR OR IMMUNOSUPPRESSION AGENTS KYOWA HAKKO KOGYO CO., LTD. (JP) 2001-11-13 — — US disclosed
US-20010027208-A1 Radicicol derivatives INO YOJI (JP) 2001-10-04 — — US disclosed
US-6239168-B1 ANTITUMOR AGENTS, IMMUNOSUPPRESSANTS; TYROSINE KINASE INHIBITORS KYOWA HAKKO KOGYO CO., LTD. (JP) 2001-05-29 — — US disclosed
CN-1211244-A Radicicol derivatives KYOWA HAKKO KOGYO KK (JP) 1999-03-17 — — CN disclosed
EP-0889042-A1 RADICICOL DERIVATIVES KYOWA HAKKO KOGYO CO., LTD. (JP) 1999-01-07 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040053990-A1 Radicicol derivatives ROS1, LYN, SRC SLC6A3 2976/4885HSP90AA1 1202/4885MAPT 4315/4885
US-20080293666-A1 Antibacterial Agents MRPL21, ABCB7, MSR1 SLC6A3 2260/4885HSP90AA1 1478/4885MAPT 4800/4885
US-20010027208-A1 Radicicol derivatives ROS1, LYN, SRC SLC6A3 3248/4885HSP90AA1 1318/4885MAPT 4314/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.