Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 14/20 | 0.83 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.72 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.37 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.37 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.37 |
| ▸ | CD74 | P04233 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10167873 | 0.91 | APP (1.00) | APPCYP1A2PDE3BPDE3AP2RY12 | |
| SCHEMBL1104925 | 0.87 | APP (0.80) | APPCYP1A2F2RL3 | |
| SCHEMBL3974521 | 0.85 | APP (0.72) | APPCYP1A2CD74MIF | |
| SCHEMBL1104922 | 0.85 | APP (0.82) | APPCYP1A2F2RL3 | |
| Ethoxyresorufin SCHEMBL104497 | 0.84 | APP (1.00) | APPCYP1A2F2RL3 | |
| Ethoxyresorufin SCHEMBL31079400 | 0.84 | APP (1.00) | APPCYP1A2F2RL3 | |
| SCHEMBL24145151 | 0.84 | APP (0.77) | APPCYP1A2F2RL3 | |
| SCHEMBL16069679 | 0.82 | APP (0.81) | APPCYP1A2F2RL3 | |
| SCHEMBL10167880 | 0.81 | APP (1.00) | APPCYP1A2MIF | |
| SCHEMBL21211676 | 0.80 | APP (0.70) | APPCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210018497-A1 | BRET SENSOR MOLECULES FOR DETECTING HYDROLASES | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2021-01-21 | — | — | US | disclosed |