SCHEMBL3974521

SCHEMBL3974521

CC(=O)Oc1ccc2nc3ccc(=O)cc-3oc2c1

nearest known ligand 0.72

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
APP P05067 13/20 0.72
CYP1A2 P05177 1/20 0.67
KDM4E B2RXH2 3/20 0.50
GLA P06280 3/20 0.50
GAA P10253 3/20 0.50
CA12 O43570 2/20 0.50
CA9 Q16790 2/20 0.50
POLB P06746 2/20 0.50
TDP1 Q9NUW8 1/20 0.50
CD74 P04233 1/20 0.47
MIF P14174 1/20 0.47
ALDH1A1 P00352 2/20 0.44
HPGD P15428 1/20 0.43
CASP1 P29466 1/20 0.43
CASP7 P55210 1/20 0.43
HSD17B10 Q99714 1/20 0.43
FLT3 P36888 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24145151 0.88 APP (0.77) APPCYP1A2KDM4EGLAGAA
SCHEMBL21211676 0.86 APP (0.70) APPCYP1A2KDM4EGLAGAA
SCHEMBL9881038 0.86 APP (0.64) APPCYP1A2KDM4EGLAGAA
SCHEMBL18932158 0.86 APP (0.74) APPCYP1A2KDM4EGAAALDH1A1
SCHEMBL22901183 0.85 APP (0.83) APPCYP1A2CD74MIF
SCHEMBL15217855 0.85 APP (0.65) APPCYP1A2KDM4EGLAGAA
SCHEMBL12189748 0.84 APP (0.67) APPCYP1A2KDM4EGLAGAA
SCHEMBL19627052 0.84 APP (0.64) APPCYP1A2KDM4EGLAGAA
SCHEMBL563392 0.84 APP (1.00) APPCYP1A2KDM4ECA12CA9
SCHEMBL31115697 0.84 APP (1.00) APPCYP1A2KDM4ECA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3894018-B1 TOPICAL, ISOTONIC COMPOSITIONS FOR GENITAL USE GLYCIOME LLC (US) 2026-04-15 EP disclosed
EP-4719594-A1 DECREASING ACINETOBACTER POPULATIONS IN THE MICROBIOME Glyciome, LLC (US) 2026-04-08 EP disclosed
US-20260076922-A1 DECREASING ACINETOBACTER POPULATIONS IN THE MICROBIOME GLYCIOME LLC (US) 2026-03-19 US disclosed
US-12576096-B2 Topical, isotonic compositions for genital use GLYCIOME, LLC (US) 2026-03-17 US disclosed
EP-4594516-A2 SYSTEMS AND METHODS FOR SCREENING OF LARGE GENE LIBRARIES President and Fellows of Harvard College (US) 2025-08-06 EP disclosed
WO-2024249580-A1 DECREASING ACINETOBACTER POPULATIONS IN THE MICROBIOME GLYCIOME, LLC (US) 2024-12-05 WO disclosed
US-12083304-B2 Kits for topical, isotonic compositions GLYCIOME, LLC (US) 2024-09-10 US disclosed
WO-2024073375-A2 SYSTEMS AND METHODS FOR SCREENING OF LARGE GENE LIBRARIES PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2024-04-04 WO disclosed
US-20230039637-A1 MICROBIOME OPTIMIZATION GLYCIOME, LLC (US) 2023-02-09 US disclosed
WO-2022246115-A1 APT1 AND APT2 INHIBITORS AND USES THEREOF CORNELL UNIVERSITY (US) 2022-11-24 WO disclosed
US-6777243-B2 MEASURING DETECTABLE SUBSTANCE BY USING AQUEOUS REACTION SYSTEM INCLUDING FORMATION REACTION OF DETECTABLE SUBSTANCE BASED ON CHEMICAL REACTION OF ANALYTE CONTAINED IN SAMPLE; REACTING IN PRESENCE OF LAYERED INORGANIC COMPOUND ARKRAY INC. (JP) 2004-08-17 US disclosed
US-20030203503-A1 Method for measuring substance and testing piece FUKUOKA TAKAO (JP) 2003-10-30 US disclosed
US-20030180183-A1 Method for measuring substance and testing piece FUKUOKA TAKAO (JP) 2003-09-25 US disclosed
US-20030175985-A1 Method for measuring substance and testing piece FUKUOKA TAKAO (JP) 2003-09-18 US disclosed
US-20030175984-A1 Method for measuring substance and testing piece FUKUOKA TAKAO (JP) 2003-09-18 US disclosed
US-20030166295-A1 Method for measuring substance and testing piece FUKUOKA TAKAO (JP) 2003-09-04 US disclosed
US-20030044316-A1 Specimen having capability of separating solid component ARKRAY INC. (JP) 2003-03-06 US disclosed
EP-1271143-A1 SPECIMEN HAVING CAPABILITY OF SEPARATING SOLID COMPONENT ARKRAY, Inc. (JP) 2003-01-02 EP disclosed
EP-0860695-A9 METHOD OF MEASUREMENT OF MATERIAL AND TESTPIECE KABUSHIKI KAISHA KYOTO DAIICHI KAGAKU (JP) 2001-10-17 EP disclosed
EP-0860695-A1 METHOD OF MEASUREMENT OF MATERIAL AND TESTPIECE KABUSHIKI KAISHA KYOTO DAIICHI KAGAKU (JP) 1998-08-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12576096-B2 Topical, isotonic compositions for genital use MAN2B2, AP1S1, MAN2A1 APP 4223/4885CYP1A2 910/4885KDM4E 4872/4885
US-20260076922-A1 DECREASING ACINETOBACTER POPULATIONS IN THE MICROBIOME MAN2B2, ALG3, FUCA1 APP 455/4885CYP1A2 151/4885KDM4E 4485/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.