Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.56 |
| ▸ | TP53 | P04637 | 5/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | CBFB | Q13951 | 1/20 | 0.56 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.54 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | CCR1 | P32246 | 2/20 | 0.52 |
| ▸ | CCR5 | P51681 | 2/20 | 0.52 |
| ▸ | CCR8 | P51685 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19603062 | 0.87 | MCHR1 (0.67) | ALDH1A1CYP3A4HPGDPDE10AMCHR1 | |
| SCHEMBL22901625 | 0.84 | PDE10A (0.56) | SMN1; SMN2TP53ALOX15HSD17B10ALDH1A1 | |
| SCHEMBL4450069 | 0.84 | MCHR1 (0.56) | SMN1; SMN2TP53ALOX15HSD17B10ALDH1A1 | |
| SCHEMBL22901618 | 0.80 | MAPT (0.52) | SMN1; SMN2HTTMEN1KMT2AMAPT | |
| SCHEMBL12817468 | 0.79 | KDM4E (0.67) | SMN1; SMN2TP53ALOX15HSD17B10ALDH1A1 | |
| SCHEMBL3245836 | 0.79 | L3MBTL1 (0.58) | SMN1; SMN2TP53ALOX15HSD17B10ALDH1A1 | |
| SCHEMBL2036823 | 0.79 | MCHR1 (0.57) | SMN1; SMN2ALOX15HSD17B10ALDH1A1HPGD | |
| SCHEMBL8889339 | 0.79 | MCHR1 (0.57) | SMN1; SMN2ALDH1A1HPGDPDE10AMCHR1 | |
| SCHEMBL19618957 | 0.78 | MEN1 (0.53) | TP53ALOX15HSD17B10ALDH1A1CYP3A4 | |
| SCHEMBL5681545 | 0.78 | SMN1; SMN2 (0.60) | SMN1; SMN2TP53ALOX15HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4686366-A1 | THE USE OF QUINOLIN-8-OLATE DERIVATIVES AND A DEVICE COMPRISING THE SAME | Noctiluca S.A. (PL) | 2026-01-28 | — | — | EP | disclosed |
| WO-2021008588-A1 | CLASS OF PYRIMIDINE QUINOLINE DERIVATIVES AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 广州新民培林医药科技有限公司 | 2021-01-21 | — | — | WO | disclosed |