Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.57 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.54 |
| ▸ | PARP1 | P09874 | 2/20 | 0.50 |
| ▸ | MIF | P14174 | 1/20 | 0.49 |
| ▸ | TDO2 | P48775 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | NQO2 | P16083 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TNKS | O95271 | 1/20 | 0.46 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.46 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19603062 | 0.87 | MCHR1 (0.67) | MCHR1PDE10AMIFNPC1NQO2 | |
| SCHEMBL4432906 | 0.84 | MAP4K4 (0.54) | MCHR1PARP1MIFNPC1NQO2 | |
| SCHEMBL4701200 | 0.84 | NPC1 (0.69) | MCHR1PDE10AMIFNPC1RAB9A | |
| SCHEMBL2036823 | 0.83 | MCHR1 (0.57) | MCHR1PDE10AMIFNQO2SMN1; SMN2 | |
| SCHEMBL28108403 | 0.79 | NPSR1 (0.48) | MCHR1MIFSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL19009931 | 0.79 | NPC1 (0.72) | PDE10ATDO2NPC1NQO2SMN1; SMN2 | |
| SCHEMBL8888504 | 0.79 | NPC1 (0.51) | PDE10ATDO2NPC1SMN1; SMN2RAB9A | |
| SCHEMBL22901540 | 0.79 | SMN1; SMN2 (0.56) | MCHR1PDE10AMIFNPC1NQO2 | |
| SCHEMBL22901625 | 0.78 | PDE10A (0.56) | MCHR1PDE10AMIFNPC1NQO2 | |
| SCHEMBL19618931 | 0.78 | MEN1 (0.56) | MCHR1MIFNPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5627193-A | MEDICAL DIAGNOSIS, CARDIOVASCULAR DIAORDERS AND PROTECTION OF ORGANS FOR TRANSPLANTATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-06 | — | — | US | disclosed |