Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 18/20 | 0.64 |
| ▸ | CHIT1 | Q13231 | 8/20 | 0.45 |
| ▸ | CHIA | Q9BZP6 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22901827 | 0.92 | KCNH2 (0.75) | KCNH2CHIT1CHIA | |
| SCHEMBL22903434 | 0.92 | KCNH2 (0.75) | KCNH2CHIT1CHIA | |
| Trifluoroacetic Acid SCHEMBL28692501 | 0.87 | KCNH2 (0.67) | KCNH2CHIT1CHIA | |
| SCHEMBL22901788 | 0.85 | KCNH2 (0.74) | KCNH2CHIT1CHIA | |
| SCHEMBL22902045 | 0.84 | KCNH2 (0.62) | KCNH2CHIT1CHIA | |
| SCHEMBL22901755 | 0.82 | KCNH2 (0.61) | KCNH2CHIT1CHIA | |
| SCHEMBL22901779 | 0.81 | KCNH2 (0.76) | KCNH2CHIT1CHIA | |
| Trifluoroacetic Acid SCHEMBL28702199 | 0.81 | KCNH2 (0.65) | KCNH2CHIT1CHIA | |
| SCHEMBL22901825 | 0.79 | KCNH2 (0.59) | KCNH2CHIT1CHIA | |
| SCHEMBL22901796 | 0.79 | KCNH2 (0.57) | KCNH2CHIT1CHIA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210015822-A1 | SUBSTITUTED AMINO TRIAZOLES USEFUL AS CHITINASE INHIBITORS | GALAPAGOS NV (BE) | 2021-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210015822-A1 | SUBSTITUTED AMINO TRIAZOLES USEFUL AS CHITINASE INHIBITORS | CHIT1, CHIA, CHI3L1 | KCNH2 3849/4885CHIT1 1/4885CHIA 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.