Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHIT1 | Q13231 | 14/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 14/20 | 0.64 |
| ▸ | CHIA | Q9BZP6 | 11/20 | 0.64 |
| ▸ | CHI3L1 | P36222 | 6/20 | 0.64 |
| ▸ | CHI3L2 | Q15782 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22901896 | 1.00 | CHIT1 (0.64) | CHIT1KCNH2CHIACHI3L1CHI3L2 | |
| Trifluoroacetic Acid SCHEMBL28700007 | 0.91 | KCNH2 (0.55) | CHIT1KCNH2CHIACHI3L1CHI3L2 | |
| SCHEMBL22901828 | 0.86 | KCNH2 (0.64) | CHIT1KCNH2CHIACHI3L1CHI3L2 | |
| SCHEMBL20747203 | 0.86 | CHIT1 (0.65) | CHIT1KCNH2CHIACHI3L1CHI3L2 | |
| SCHEMBL18589460 | 0.86 | CHIT1 (0.65) | CHIT1KCNH2CHIACHI3L1CHI3L2 | |
| SCHEMBL22903464 | 0.86 | KCNH2 (0.64) | CHIT1KCNH2CHIACHI3L1CHI3L2 | |
| SCHEMBL18577280 | 0.86 | CHIT1 (0.65) | CHIT1KCNH2CHIACHI3L1CHI3L2 | |
| SCHEMBL23169726 | 0.85 | CHIA (0.64) | CHIT1KCNH2CHIACHI3L1CHI3L2 | |
| SCHEMBL18609554 | 0.85 | CHIA (0.64) | CHIT1KCNH2CHIACHI3L1CHI3L2 | |
| SCHEMBL18608039 | 0.85 | CHIA (0.64) | CHIT1KCNH2CHIACHI3L1CHI3L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021009209-A1 | SUBSTITUTED AMINO TRIAZOLES USEFUL AS CHITINASE INHIBITORS | Oncoarendi Therapeutics S.A. (PL) | 2021-01-21 | — | — | WO | disclosed |