Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22904386 | 0.80 | CHRNA7 (0.42) | ALDH1A1HTTCA12CA1CA2 | |
| SCHEMBL64018 | 0.79 | ALDH1A1 (0.57) | ALDH1A1L3MBTL1GRM2SMN1; SMN2NPC1 | |
| SCHEMBL2953402 | 0.78 | ALDH1A1 (0.56) | ALDH1A1GRM2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL22904242 | 0.77 | SMYD3 (0.54) | SMN1; SMN2NPC1RAB9AGAAMAPT | |
| SCHEMBL25141591 | 0.76 | ALDH1A1 (0.54) | ALDH1A1GRM2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL26648212 | 0.76 | ALDH1A1 (0.57) | ALDH1A1GRM2SMN1; SMN2LMNANPC1 | |
| SCHEMBL10861127 | 0.76 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL22904385 | 0.74 | KMT2A (0.53) | ALDH1A1L3MBTL1SMN1; SMN2LMNAMAPT | |
| SCHEMBL2948394 | 0.74 | L3MBTL1 (0.64) | ALDH1A1L3MBTL1SMN1; SMN2PKMNPC1 | |
| SCHEMBL28884226 | 0.73 | ALDH1A1 (0.58) | ALDH1A1GRM2SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021011631-A1 | FUSED-GLUTARIMIDE CRBN LIGANDS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2021-01-21 | — | — | WO | disclosed |