Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4709618 | 0.84 | ALDH1A1 (0.51) | ALDH1A1TSHRHPGDMAPK1HSD17B10 | |
| SCHEMBL6831699 | 0.84 | ALDH1A1 (0.51) | ALDH1A1TSHRHPGDMAPK1HSD17B10 | |
| SCHEMBL1344119 | 0.84 | ALDH1A1 (0.51) | ALDH1A1TSHRHPGDMAPK1HSD17B10 | |
| SCHEMBL191353 | 0.83 | LMNA (0.55) | EPHX2EPHX1ALDH1A1LMNACYP1A2 | |
| SCHEMBL8947886 | 0.83 | LMNA (0.55) | EPHX2EPHX1ALDH1A1LMNACYP1A2 | |
| Hydrochloric Acid SCHEMBL1835887 | 0.81 | LMNA (0.53) | EPHX2EPHX1ALDH1A1LMNACYP1A2 | |
| SCHEMBL20730059 | 0.78 | ALDH1A1 (0.56) | ALDH1A1TSHRHPGDLMNASIGMAR1 | |
| SCHEMBL1206984 | 0.78 | — | — | |
| SCHEMBL23106 | 0.78 | — | — | |
| SCHEMBL24424509 | 0.75 | HPGD (0.63) | EPHX1ALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021010492-A1 | COMPOUND HAVING KDM5 INHIBITORY ACTIVITY AND PHARMACEUTICAL USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2021-01-21 | — | — | WO | disclosed |