SCHEMBL22904895

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29443061	1.00	CHEK2 (0.48)	CHEK2MAPK1MCL1F2F10
	SCHEMBL22904894	0.92	MCL1 (0.43)	CHEK2MAPK1MCL1STING1VDR
	SCHEMBL29443069	0.92	MCL1 (0.43)	CHEK2MAPK1MCL1STING1VDR
	SCHEMBL22905022	0.88	KDM4E (0.52)	CHEK2MAPK1F2F10PLG
	SCHEMBL29693898	0.88	KDM4E (0.52)	CHEK2MAPK1F2F10PLG
	SCHEMBL29443113	0.88	KDM4E (0.52)	CHEK2MAPK1F2F10PLG
	SCHEMBL24772449	0.84	JAK2 (0.50)	MAPK1MCL1
	SCHEMBL24771134	0.82	JAK2 (0.52)	MAPK1MCL1STING1
	SCHEMBL24771131	0.82	JAK2 (0.52)	MAPK1MCL1STING1
	SCHEMBL22904893	0.81	KDM4E (0.52)	CHEK2MAPK1STING1VDRNR1H4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.