Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHF8 | Q9UPP1 | 7/20 | 0.48 |
| ▸ | KDM2A | Q9Y2K7 | 7/20 | 0.48 |
| ▸ | KDM5C | P41229 | 5/20 | 0.48 |
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | KDM6B | O15054 | 3/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.38 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.38 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | GNPAT | O15228 | 1/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL93970 | 0.74 | — | — | |
| SCHEMBL14798778 | 0.72 | PHF8 (0.43) | PHF8KDM2AKDM5CEGLN1KDM4E | |
| SCHEMBL9076736 | 0.70 | PHF8 (0.50) | PHF8KDM2AKDM5CEGLN1KDM4E | |
| SCHEMBL9618339 | 0.69 | TSHR (0.48) | PHF8KDM2AKDM5CEGLN1KDM4E | |
| SCHEMBL14798439 | 0.69 | PHF8 (0.45) | PHF8KDM2AKDM5CEGLN1KDM4E | |
| Succinic Acid SCHEMBL5875205 | 0.68 | EGLN1 (0.69) | PHF8KDM2AKDM5CEGLN1KDM4E | |
| Succinic Acid SCHEMBL5875196 | 0.68 | EGLN1 (0.69) | PHF8KDM2AKDM5CEGLN1KDM4E | |
| SCHEMBL9707584 | 0.67 | — | — | |
| SCHEMBL21254183 | 0.67 | PHF8 (0.52) | PHF8KDM2AKDM5CEGLN1KDM4E | |
| SCHEMBL27641272 | 0.67 | PHF8 (0.52) | PHF8KDM2AKDM5CEGLN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020006423-A9 | SYNTHETIC GUIDE MOLECULES, COMPOSITIONS AND METHODS RELATING THERETO | EDITAS MEDICINE, INC. (US) | 2021-01-21 | — | — | WO | disclosed |