Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | KDM5C | P41229 | 2/20 | 0.45 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.45 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PLG | P00747 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28090046 | 0.89 | TSHR (0.44) | TSHRLMNANFKB1PMP22ALDH1A1 | |
| SCHEMBL8362365 | 0.85 | GPR84 (0.59) | TSHRLMNAALDH1A1MEN1ALOX15 | |
| SCHEMBL8341881 | 0.84 | GPR84 (0.57) | TSHRLMNAALDH1A1MEN1ALOX15 | |
| SCHEMBL15650442 | 0.84 | GPR84 (0.57) | TSHRALDH1A1MEN1ALOX15KMT2A | |
| SCHEMBL8336748 | 0.84 | GPR84 (0.57) | TSHRLMNAALDH1A1MEN1ALOX15 | |
| SCHEMBL15649652 | 0.84 | GPR84 (0.57) | TSHRALDH1A1MEN1ALOX15KMT2A | |
| SCHEMBL22151180 | 0.82 | GPR84 (0.53) | TSHRALDH1A1MEN1ALOX15KMT2A | |
| SCHEMBL27524961 | 0.82 | HDAC3 (0.34) | TSHRLMNAALDH1A1KDM4EMEN1 | |
| SCHEMBL27645896 | 0.79 | TSHR (0.36) | TSHRLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL8423003 | 0.76 | HSP90AA1 (0.55) | LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4325088-A | — | — | None | — | — | JP | disclosed |
| JP-H04325088-A | PROTEIN DERIVATIVE AND PRODUCTION THEREOF | KURARAY CO LTD | 1992-11-13 | — | — | JP | disclosed |