Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.50 |
| ▸ | HTR3B | O95264 | 2/20 | 0.50 |
| ▸ | HTR3A | P46098 | 2/20 | 0.50 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.50 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.50 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.50 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.50 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.50 |
| ▸ | PLAU | P00749 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8047214 | 1.00 | HTR3E (0.50) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL7870702 | 0.91 | HTR3E (0.58) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL7870699 | 0.91 | HTR3E (0.58) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL30102029 | 0.91 | HTR3E (0.58) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL11038706 | 0.85 | MAPT (0.59) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL11038702 | 0.85 | MAPT (0.59) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL8139110 | 0.85 | ESR1 (0.61) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL29779865 | 0.85 | MAPT (0.59) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL8139108 | 0.85 | ESR1 (0.61) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL28234597 | 0.81 | GSK3B (0.53) | HTR3EHTR3BHTR3AHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696269-B1 | PROCESS FOR PREPARING SUBSTITUTED AROMATIC AMINES | MONSANTO CO (US) | 1999-06-30 | — | — | EP | claimed |
| US-5633407-A | Process for preparing substituted aromatic amines | FLEXSYS AMERICA L. P. (US) | 1997-05-27 | — | — | US | claimed |
| EP-0641313-B1 | PROCESS FOR PREPARING SUBSTITUTED AROMATIC AMINES | MONSANTO CO (US) | 1997-01-22 | — | — | EP | claimed |
| US-5552531-A | USED IN THE PRODUCTION OF AROMATIC AMINES, REACTING A NUCLEOPHILIC ANILINE, OR AMIDE OR AMINE WITH AN AZO COMPOUND | MONSANTO COMPANY (US) | 1996-09-03 | — | — | US | claimed |
| US-5451702-A | Process for preparing substituted aromatic amines | MONSANTO COMPANY (US) | 1995-09-19 | — | — | US | claimed |
| EP-0641313-A1 | PROCESS FOR PREPARING SUBSTITUTED AROMATIC AMINES. | MONSANTO CO (US) | 1995-03-08 | — | — | EP | claimed |
| WO-1993024450-A1 | PROCESS FOR PREPARING SUBSTITUTED AROMATIC AMINES | MONSANTO COMPANY (US) | 1993-12-09 | — | — | WO | claimed |
| US-9895094-B2 | Lateral flow device for attachment to an absorbent article | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2018-02-20 | — | — | US | disclosed |
| US-9194807-B2 | Multi-layered devices for analyte detection | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2015-11-24 | — | — | US | disclosed |
| US-20150260658-A1 | Multi-Layered Devices for Analyte Detection | KIMBERLY CLARK CO (US) | 2015-09-17 | — | — | US | disclosed |
| US-9103796-B2 | Multi-layered devices for analyte detection | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2015-08-11 | — | — | US | disclosed |
| EP-1920067-B1 | ENZYME DETECTION TECHNIQUE | KIMBERLY CLARK CO (US) | 2015-06-03 | — | — | EP | disclosed |
| US-20150025347-A1 | Lateral Flow Device for Attachment to an Absorbent Article | KIMBERLY-CLARK WORLDWIDE, INC. | 2015-01-22 | — | — | US | disclosed |
| WO-1994008953-A1 | PROCESS FOR PREPARING ISOCYANATE AND CARBAMATE ESTER PRODUCTS | MONSANTO COMPANY (US) | 1994-04-28 | — | — | WO | disclosed |
| WO-1993024450-A1 | PROCESS FOR PREPARING SUBSTITUTED AROMATIC AMINES | MONSANTO COMPANY (US) | 1993-12-09 | — | — | WO | disclosed |
| US-5233010-A | Reacting carbon dioxide and an aromatic diamine in an aprotic solvent and a base to produce a carbamate salt; dehydration; reacting an amide with nitrobenzene and reducing to obtain the amine | MONSANTO COMPANY (US) | 1993-08-03 | — | — | US | disclosed |
| EP-0138750-B1 | PROCESS FOR THE PRODUCTION OF SUBSTITUTED BENZIMIDAZOLES | CIBA-GEIGY AG (CH) | 1987-09-09 | — | — | EP | disclosed |
| EP-0138760-B1 | PROCESS FOR THE PREPARATION OF N-SUBSTITUTED ORTHO-PHENYLENE-DIAMINES | CIBA-GEIGY AG (CH) | 1986-12-10 | — | — | EP | disclosed |
| EP-0138760-A1 | Process for the preparation of N-substituted ortho-phenylene-diamines | CIBA-GEIGY AG (CH) | 1985-04-24 | — | — | EP | disclosed |
| EP-0138750-A1 | Process for the production of substituted benzimidazoles | CIBA-GEIGY AG (CH) | 1985-04-24 | — | — | EP | disclosed |