SCHEMBL7870702

SCHEMBL7870702

Clc1cccc(N=Nc2cccc(Cl)c2)c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR3E A5X5Y0 2/20 0.58
HTR3B O95264 2/20 0.58
HTR3A P46098 2/20 0.58
HTR3D Q70Z44 2/20 0.58
HTR3C Q8WXA8 2/20 0.58
SLC22A2 O15244 1/20 0.58
SLC22A1 O15245 1/20 0.58
SLC22A3 O75751 1/20 0.58
PLAU P00749 1/20 0.58
MAPT P10636 5/20 0.55
GAA P10253 1/20 0.55
KMT2A Q03164 6/20 0.51
MEN1 O00255 5/20 0.51
IDO1 P14902 1/20 0.51
TDO2 P48775 1/20 0.51
RAB9A P51151 1/20 0.51
CYP2D6 P10635 2/20 0.50
TSHR P16473 2/20 0.50
CYP2C9 P11712 2/20 0.50
GSK3B P49841 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30102029 1.00 HTR3E (0.58) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL7870699 1.00 HTR3E (0.58) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL8047214 0.91 HTR3E (0.50) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL2290645 0.91 HTR3E (0.50) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL8139108 0.85 ESR1 (0.61) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL29779865 0.85 MAPT (0.59) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL8139110 0.85 ESR1 (0.61) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL28234597 0.85 GSK3B (0.53) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL11038706 0.85 MAPT (0.59) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL11038702 0.85 MAPT (0.59) HTR3EHTR3BHTR3AHTR3DHTR3C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113480485-B 1,2, 4-triaryl-1, 2, 4-triazoles compound and synthetic method thereof 甘肃农业大学 2023-04-07 CN disclosed
CN-111978201-B Synthesis method of N, N' -diaryl benzoyl hydrazine compound 甘肃农业大学 2023-01-03 CN disclosed
CN-113480485-A 1,2, 4-triaryl-1, 2, 4-triazoles compound and synthetic method thereof 甘肃农业大学 2021-10-08 CN disclosed
CN-111978201-A Synthesis method of N, N' -diaryl benzoyl hydrazine compound 甘肃农业大学 2020-11-24 CN disclosed
CN-108273478-A A kind of formaldehyde removing composition and product 李怀玉 2018-07-13 CN disclosed
US-6316589-B1 FOR USE IN MANUFACTURING OPTICAL WAVEGUIDES SAMSUNG ELECTRONICS CO., LTD (KR) 2001-11-13 US disclosed
EP-0138750-B1 PROCESS FOR THE PRODUCTION OF SUBSTITUTED BENZIMIDAZOLES CIBA-GEIGY AG (CH) 1987-09-09 EP disclosed
EP-0138750-A1 Process for the production of substituted benzimidazoles CIBA-GEIGY AG (CH) 1985-04-24 EP disclosed
EP-0001479-A2 Process for the preparation of nitrophenylhydroxyacetylene and conversion to nitrophenylacetylene GULF RESEARCH & DEVELOPMENT COMPANY (US) 1979-04-18 EP disclosed
US-4128588-A PALLADIUM-PHOSPHINE COMPLEX CATALYST GULF RESEARCH & DEVELOPMENT COMPANY (US) 1978-12-05 US disclosed
US-4058607-A DIHALOVINYL DIALKYL PHOSPHATE, 1,3-BENZODIOXOLES AIRWICK INDUSTRIES, INC. (US) 1977-11-15 US disclosed
US-3966900-A INSECTICIDES AIRWICK INDUSTRIES, INC. (US) 1976-06-29 US disclosed