Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 18/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22907106 | 0.86 | OPRK1 (0.37) | OPRK1 | |
| SCHEMBL24670690 | 0.78 | PDE10A (0.48) | OPRK1ACACB | |
| SCHEMBL30066350 | 0.78 | PDE10A (0.48) | OPRK1ACACB | |
| SCHEMBL22907440 | 0.75 | OPRK1 (0.45) | OPRK1ACACB | |
| SCHEMBL31583655 | 0.74 | OPRK1 (0.44) | OPRK1ACACB | |
| SCHEMBL22907270 | 0.74 | OPRK1 (0.44) | OPRK1ACACB | |
| SCHEMBL27098930 | 0.73 | OPRK1 (0.41) | OPRK1ACACB | |
| SCHEMBL24881373 | 0.73 | OPRK1 (0.44) | OPRK1ACACB | |
| SCHEMBL17316555 | 0.71 | HTT (0.41) | OPRK1ACACB | |
| SCHEMBL20354132 | 0.71 | OPRK1 (0.40) | OPRK1ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021011913-A1 | TAU-PROTEIN TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2021-01-21 | — | — | WO | disclosed |