Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20120567 | 0.80 | PRMT5 (0.39) | HCAR2GRM5 | |
| SCHEMBL29773839 | 0.80 | PRMT5 (0.39) | HCAR2GRM5 | |
| SCHEMBL20129151 | 0.73 | HCAR2 (0.40) | HCAR2GRM5 | |
| SCHEMBL18101462 | 0.69 | FFAR1 (0.41) | — | |
| SCHEMBL20213850 | 0.68 | KDM4C (0.40) | HCAR2GRM5 | |
| SCHEMBL29547563 | 0.68 | KDM4C (0.40) | HCAR2GRM5 | |
| SCHEMBL20120643 | 0.68 | KDM4C (0.40) | HCAR2GRM5 | |
| SCHEMBL4178339 | 0.63 | ESR1 (0.41) | MIF | |
| SCHEMBL30824737 | 0.63 | GPR119 (0.47) | — | |
| SCHEMBL22369545 | 0.62 | MIF (0.34) | MIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021011913-A1 | TAU-PROTEIN TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2021-01-21 | — | — | WO | disclosed |