SCHEMBL30824737

SCHEMBL30824737

CC(C)(C)OC(=O)N1CCC(C#Cc2ccc(O)cn2)CC1

nearest known ligand 0.47

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 14/20 0.47
KMT2A Q03164 1/20 0.44
HPGDS O60760 1/20 0.42
PTPN2 P17706 1/20 0.42
PTPN1 P18031 1/20 0.42
PTPN6 P29350 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27391936 0.87 ALDH1A1 (0.52) GPR119KMT2A
SCHEMBL24233245 0.87 GPR119 (0.50) GPR119KMT2AHPGDS
SCHEMBL27007401 0.85 GPR119 (0.48) GPR119KMT2AHPGDS
SCHEMBL16973168 0.84 ALDH1A1 (0.51) GPR119HPGDS
SCHEMBL27313243 0.82 GPR119 (0.59) GPR119
SCHEMBL30812264 0.81 GPR119 (0.55) GPR119
SCHEMBL30376767 0.77 GPR119 (0.50) GPR119KMT2AHPGDS
SCHEMBL25169929 0.77 GPR119 (0.50) GPR119KMT2AHPGDS
SCHEMBL1199881 0.77 GPR119 (0.58) GPR119HPGDSPTPN2PTPN1PTPN6
SCHEMBL30490329 0.76 GPR119 (0.45) GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250388575-A1 HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE HALDA THERAPEUTICS OPCO INC (US) 2025-12-25 US disclosed
WO-2024054955-A1 HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE HALDA THERAPEUTICS OPCO, INC. (US) 2024-03-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250388575-A1 HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, HCCS, CBR1 GPR119 1811/4885KMT2A 3050/4885HPGDS 811/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.